单选题 Despite of their opposition, he went his own way and started his preparations.
【正确答案】 C
【答案解析】[解析] 本题考查介词的用法。句意为:不管他们的反对,他动身并开始准备工作。本句中的despite为介词,其后可直接跟名词短语。所以,答案为C。