单选题 During a routine follow-up examination, the nurse updates the client’s medication history. The client currently receives prednisone therapy. Concomitant use of an agent from which of the following classes could increase the risk of peptic ulcer disease（）

A、 Antidiabetic agents, administered orally.
B、 Nonsteroidal anti-inflammatory drugs (NSAIDs).
C、 Beta-adrenergic blockers.
D、 Contraceptive agents, administered orally.

【正确答案】 B

【答案解析】Concomitant use of NSAIDs may increase the risk of a peptic ulcer; therefore, they should be administered 2 hours before or 2 hours after prednisone. Oral antidiabetic agents, beta-adrenergic blockers, and oral contraceptive agents don’t increase the risk of peptic ulcer disease when administered with prednisone.