_____, I will spare no effort to persuade him to go abroad for further study.
【正确答案】 B
【答案解析】引导让步状语从句的副词或连词的用法。however和though可以引导让步状语从句,但用法不同。however需与形容词或副词连用,表示对其进行强调,结构为“however hard+主语+谓语”,意为“不管如何努力……”,因此选B。D的词序不对,though是一个连词,需引导完整的句子作状语从句。A和C选项的词序都不对,应为though the work is hard或hard though the work is。