【正确答案】 B

【答案解析】[解析] 那个错误使他找工作成为泡影。句中ruin：毁灭。reduce：降低，如：They've reduced the prices in the shop, so it's a good time to buy．商店已经降低了商品的价格，看来现在是买东西的好时候。destroy：破坏，如：The fire destroyed all my books．这场大火毁了我的全部书籍。deny：否认，如：He said that I had stolen his bicycle, but I denied it．他说我偷了他的自行车，可是我否认了lose：丢失，如：I cannot find my watch; I must have lost it．我找不到手表，我一定把它给丢了。和his chances搭配时，只有destroy意思上和ruin最接近。