Little______about her own safety, though she herself was in great danger.
she cared
she may care
may she care
did she care
解析：此句中it作形式宾语接在谓语动词之后，用that引导从句be should have leftwithout telling anyone beforehand作真正的宾语接在其后，构成“动词+it+补语+that宾语从句”结构。因此D为答案。