单选题 American researchers are working on three antibodies that many mark a new step on the path toward an HIV vaccine, according to a report published online Thursday, July 8, 2010, in the journal Science. One of the antibodies suppresses 91 percent of HIV strains, more than any AIDS antibody ever discovered, according to a report on the findings published in the Wall Street Journal. The antibodies were discovered in the cells of a 60-year-old African-American gay man whose body produced them naturally. One antibody in particular is substantially different from its precursors, the Science study says. The antibodies could be tried as a treatment for people already infected with HIV, the WSJ reports. At the very least, they might boost the efficacy of current antiretroviral drugs. It is welcome news for the 33 million people the United Nations estimated were living with AIDS at the end of 2008. The WSJ outlines the painstaking method the team used to find the antibody amid the cells of the African-American man, known as Donor 45. First they designed a probe that looks just like a spot on a particular molecule on the cells that HIV infects. They used the probe to attract only the antibodies that efficiently attack that spot. They screened 25 million of Donor 45's cell to find just 12 cells that produced the antibodies. Scientists have already discovered plenty of antibodies that either don't work at all or only work on a couple of HIV strains. Last year marked the first time that researchers found "broadly neutralizing antibodies, " which knock out many HIV strains. But none of those antibodies neutralized more than about 40 percent of them, the WSJ says. The newest antibody, at 91 percent neutralization, is a marked improvement. Still, more work needs to be done to ensure the antibodies would activate the immune system to produce natural defenses against AIDS, the study authors say. They suggest three test methods that blend the three new antibodies together in raw form to prevent transmission of the virus, such as from mother to child; in a microbicide gel that women or gay men could use before sex to prevent infection; or as a treatment for HIV/AIDS, combined with antiretroviral drug. If the scientists can find the right way to stimulate production of the antibodies, they think most people could produce then, the WSJ says.
单选题 We can learn from the beginning of the passage that______.
【正确答案】 A
【答案解析】解析:细节题。题干:从文中开头我们可以得知______。根据文章前两段的内容,可知A选项(一种新发现的抗体能打败91%的HIV病毒)是最合适的答案。B选项(一种新的抗逆转录病毒药物已经上市)、C选项(美国研究者已经研发出抵抗HIV的新疫苗)、D选项(一个非裔美国同性恋男士被从HIV感染中治愈)均不吻合原文信息。
单选题 What is the implication of the antibodies discovered in the cells of the African-American gay man?
【正确答案】 B
【答案解析】解析:细节题。题干:在非裔美国同性恋男士的细胞中发现的抗体有什么意义?用African-American回到原文定位到第二段最后两句话:这种抗体可用来治疗HIV病毒感染者。至少会增强抗逆转录病毒药物的功效。因此本题正确答案为B。
单选题 The newest antibody found in Donor 45 reflects a dramatic advance in terms of______.
【正确答案】 C
【答案解析】解析:细节题。题干:在Donor 45中新发现的抗体反映了在______的巨大进步。从倒数第三段最后一句…neutralization,is a marked improvement可知,这里marked improvement与题干中dramatic advance是同义改写的关系。故本题答案为C。
单选题 According to the study authors, the three test methods are intended to______.
【正确答案】 B
【答案解析】解析:细节题。题干:根据该研究作者的观点,三种测试方法旨在______。从文中倒数第二段可知,他们建议把三种新的抗体混合在一起,不经其他加工来防止病毒的传播。即通过自然的免疫防御来抵制艾滋病。故本题答案为B。
单选题 The passage is most likely______.
【正确答案】 B
【答案解析】解析:推理题。题干:本文很可能是______。根据第一段可知,本文有可能是一篇科学论文,记录艾滋病防治的最新进展和突破。因此,B项的可能性最大。新闻报道往往不涉及如此深刻的理论分析,教科书则重在经典理论知识而非最新研究,科幻小说更是背道而驰。故本题答案为B。