单选题 Which of the following signs and symptoms is classic for a patient with rheumatoid arthritis?
A. Joint swelling, joint stiffness in the morning, and bilateral joint involvement.
B. Crepitus, development of Heberden's nodes, and anemia.
C. Pain on weight-bearing, rash, and low-grade fever.
D. Fatigue, leukopenia, and joint pain.

【正确答案】 A
【答案解析】Classic signs and symptoms of rheumatoid arthritis include joint pain, swelling, and warmth. Symptoms are typically bilaterally symmetric. Joint stiffness in the morning lasting longer than 30 minutes is another classic symptom. Rheumatoid arthritis is a systemic disease. Other symptoms can include fatigue, low-grade fever, anemia, and weight loss.