填空题
{{B}} A = Superficial Spreading Melanoma
B =
Nodular Melanoma
C = Lentigo Maligna Melanoma
D = Acral Lentiginous Melanoma
Which type(s) has/ve the trait
that ...{{/B}}
Melanoma, also referred to as "malignant melanoma", is the
most serious form of skin cancer. It is the skin cancer most likely to spread to
lymph nodes and internal organs. There are four most common types of melanoma,
which accounts for about 100% of diagnosed cases.
{{B}}A{{/B}}
{{B}}Superficial Spreading Melanoma:{{/B}}
Superficial spreading melanoma (SSM) is the most common type of melanoma in the
United States, accounting for about 70% of all diagnosed melanoma cases. This
type of melanoma can strike at any age and occurs slightly more often in females
than males. SSM is the leading cause of death from cancer in young
adults.
When SSM occurs in females, it most commonly appears on
the legs. In males, it is more likely to develop between the neck and pelvis.
However, this does not mean that females do not get SSM on their trunks or that
males do not see SSM on their legs. This melanoma can occur anywhere on the
skin's surface.
A typical SSM lesion has irregular borders and
various shades of black, brown, gray, blue, pink, red, or white. Within the
lesion there can be a remarkable variation in color involving white, pink,
brown, and black.
In the early stages, SSM usually appears as a
flat spot that looks like a freckle that is spreading sideways on the skin. Over
time, the pigmentation in the lesion may darken, and the lesion may grow,
develop increasingly irregular borders, and have areas of inflammation within
the lesion. The area around the lesion may begin to itch. Occasionally, a SSM
may become "less" pigmented as a person's immune responses try to destroy
it.
Superficial spreading melanoma can progress
rapidly.
{{B}}B{{/B}}
{{B}}Nodular Melanoma:{{/B}} Nodular melanoma (NM) is the
most aggressive type of melanoma and accounts for about 15% of all melanomas
diagnosed in the United States. It can appear anywhere on the body and occurs
more often in males than females. It can develop at any age; however, it is most
often seen in people aged 60 and older.
NM is different from
other types of melanoma. It tends to grow more rapidly in thickness than in
diameter and it may not have a readily visible phase of development. Instead of
arising from a pre-existing mole, it may appear in a spot where a lesion did not
previously exist.
Since NM tends to grow deeper more quickly
than it does wide and can occur in a spot that did not have a previous lesion,
the prognosis is often worse because it takes longer for a person to be aware of
the changes.
NM is most often darkly pigmented; however, some NM
lesions can be light brown or even colorless (non-pigmented). A light-colored or
non-pigmented NM lesion may escape detection because the appearance is not
alarming. An ulcerated and bleeding lesion is common.
{{B}}C{{/B}}
{{B}}Lentigo Maligna
Melanoma:{{/B}} Lentigo maligna melanoma (LMM) typically occurs on sun-damaged
skin in the middle-aged and elderly, especially on the face. This melanoma may
be mistaken in its early, and most treatable, stages for a benign "age spot" or
"sun spot". LMM accounts for about 10% of the melanomas diagnosed in the United
States. Since LMM is so easily mistaken, it can go undetected for years. This
can be quite dangerous.
LMM begins as a spreading, flat, patch
with irregular borders and variable colors of brown. This lesion is called
"lentigo rnaligna". This spreading brownish patch may grow slowly for years and
is often mistaken for lentigo simplex—a benign (non cancerous) brownish patch
that can develop in the elderly after years of sun exposure.
As
the lesion grows and evolves, both the pigmentation and borders tend to become
more irregular. This often occurs slowly over a period of 10 to 15 years. It
also can happen rapidly--in a matter of weeks or months. As the lesion grows
deeper into the skin (thickness increases), it may become various shades of
black and brown. Dark nodules may appear within the irregular borders. These
nodules me the invasive tumor, and if large enough to be felt by touch, will
feel lumpy.
{{B}}D{{/B}}
{{B}}Acral Lentiginous Melanoma:{{/B}} In the United States, acral lentiginous
melanoma (ALM) accounts for about 5% of all diagnosed melanomas. It also is the
most common form of melanoma in Asians and people with dark skin, accounting for
50% of melanomas that occur in people with these skin types.
ALM
is sometimes referred to as a "hidden melanoma" because these lesions occur on
parts of the body not easily examined or not thought necessary to examine. ALM
develops on the palms, soles, mucous membranes (such as those that line the
mouth, nose, and female genitals), and underneath or near fingernails and
toenails.
ALM is often overlooked until it is well advanced
because in the early stages, it often looks like a bruise or nail
streak.
As an ALM tumor increases in size, it usually becomes
more irregular in shape and color. However, some ALM lesions can be lightly
colored or colorless. The surface of the ALM lesion may remain flat, even as the
rumor invades deeply into the skin. Thickening ALM on the sole of the foot can
make walking painful and be mistaken for a plantar wart.
· it is the most
common form of melanoma in people of color?
71.
______
· this type of melanoma occurs more often in males than females?
72. ______
· dark nodules may appear within the irregular
borders of the lesions?
73. ______
· it may develop on mucous membranes?
74. ______
· it can occur anywhere on the skin's surface?
75.
______
76. ______
· this type of melanoma occurs more often in
females than males?
77. ______
· it often looks like a bruise
or nail streak in the early stages?
78. ______
· it can develop on
sun-damaged skin especially on the face?
79.
______
· it looks like a freckle that is spreading sideways on the skin in
the early stages? 80. ______