单选题 4.  Once Manchester was the home of the most productive cotton mills in the world. The underlined part means ______.
【正确答案】 C
【答案解析】 该题是词汇题,考查介词短语的意义和用法。
   题干中划线部分的意思是“曾经”。在四个选项中,只有选项C中的at one time表示“过去曾经”,如:At one time hospital doctors were men, but today there are many women doctors as well. 过去医生都是男的,现在也有很多女医生了。其他几个搭配是错误的。因此,选项C为最佳答案。