单选题 John likes music very much, but when he went to university he decided to study medicine ______ of music.
A. despite B. instead
C. in places D. in spite

【正确答案】 B

【答案解析】[考点] 介词短语辨异。despite of不管，不论；instead of代替，而不是；in place of代替，意思与instead of相同，而无in places of结构；in spite of不管，不顾。故选B。