{{B}}
New Attempts to Eradicate AIDS Virus{{/B}}
A high-profile attempt to eradicate the AIDS virus in a few patients
continues to show promise. But researchers won't know for a year
or more whether it will work, scientist David Ho told journalists this Wednesday
for the Fourth Conference in Viruses and Infections. "This is a
study that's in progress," says Ho, head of the Aaron Diamond AIDS Research
Center, New York. The study involves 20 people who started
combinations of anti-HIV drugs very early in the course of the disease, within
90 days of their infections. They've been treated for up to 18 months. Four
others have dropped out because of side effects or problems complying with the
exacting drug system. The drugs have knocked the AIDS virus down
to undetectable levels in the blood of all remaining patients. And, in the
latest development, scientists have now tested lymph nodes and semen from a few
patients and found no virus reproducing there, Ho says. "Bear in mind that
undetectable does not equal absent," Ho says. Ho has calculated
that the drugs should be able to wipe out remaining viruses--at least from known
reservoirs throughout the body--in two to three years. But the only way to prove
eradication would be to stop the drugs and see if the virus comes back. On
Wednesday, Ho said he wouldn't ask any patient to consider that step before 2
years of treatment. And he emphasized that he is not urging
widespread adoption of such early, aggressive treatment outside of trials. No
one knows the long-term risks. But other scientists are looking
at similar experiments. A federally funded study will put 300 patients on
triple-drug treatments and then see if some responding well after six months can
continue to suppress the virus on just one or two drugs, says researcher Douglas
Richman of the University of California, San Diego. Some patients in that study
'also may be offered the chance to stop therapy after 18 months or more, he
says.
单选题
According to the passage, the attempt to eradicate the AIDS virus
【正确答案】
A
【答案解析】[解析] 利用题干中的核心词“the attempt”作为答案线索，同时注意利用备选项中的核心词“hopeful”和“successful”，发现答案相关句：A high-profile attempt to eradicate the AIDS virus in a few patients continues to show promise(与A中的hopeful呼应)。这个句子说“为消除一些病人身体中的AIDS病毒所做的尝试一直显示出希望”，根据这句话的内容判断A(一直显现出希望)是答案。
单选题
Which is NOT true about the study?
【正确答案】
D
【答案解析】[解析] 这是“是非判断”题，这类问题在解题过程中必须充分利用备选项的结构、句意和用词特点。本题中所给的备选项中出现了病人人数和时间，因此注意文章中涉及到病人人数和时间的句子，这样找到答案相关句：The study involves 20 people (说明A正确：有20个人参与实验)who started combinations of anti-HIV drugs(说明B正确：在疾病早期阶段使用过集中抗HIV药品)very early in the course of the disease，within 90 days of their infections．They've been treated for up to 18 months (说明C正确)Four others have dropped out (该结构说“另外行四个人退出”，因此参加完整个实验的有16人，因此D错误)because of side effects or problems complying with the exacting drug system． drop out v．不参与，离去，放弃
单选题
What do Ho's words "Bear in mind that undetectable does not equal absent" mean?
单选题
How could we prove that the drugs have wiped out the remaining viruses?
【正确答案】
D
【答案解析】[解析] 该题可直接借助常识判断答案D合理。也可以借助原文：利用题干中的核心短语“wiped out”作为答案线索，发现答案相关句：He has calculated that the drugs should be able to wipe out remaining viruses—at least from known reservoirs(储主)throughout the body—two to three years，But the only way to prove eradication(与wiped out是近义词)would be to stop the drugs and see if the virus comes back．该句说“证明是否彻底消灭了病毒的惟一方法就是观察停药后病毒是否会卷土重来。”因此D是答案。 wipe out v．消灭，垮台
单选题
Other scientists are looking at experiments that are similar in that they are______.
【正确答案】
D
【答案解析】[解析] 利用题干中的特征结构(修饰结构)“Other scientists”和“similar”作为答案线索，发现答案相关句：And he emphasized that he is not urging widespread adoption of such early, aggressive treatment outside of trials．No one knows the long-term risks．But other scientists ale looking at similar experiments．But的出现表明But的前后句在句意上紧密相关，所以注意But的前句内容，该句说“没有人知道长期的风险”，该句内容暗示类似的实验是存在很大风险的，对比备选项判断只有D“大胆的(实验)”最可能是答案，而且前面的句子中还出现了aggressive(把这种治疗方法称作“挑战性的治疗方案”)，综合这些分析，确认D是答案。