填空题.Depression is one of the most common health disorders in the U. S. and heart disease is a leading cause of death. "Although they can and do occur 41 , research shows that the two conditions are often connected, " health experts write in the February 42 of the Mayo Clinic Women's Health Source. Previous studies have shown that depression is more 43 among people with heart disease than among those without. Researchers found that one in three heart attack 44 experience depression, compared to about one in twenty adults in the general population. Explaining the connection between the two conditions, the Mayo Clinic experts note that depression 45 not only the mind but also physical health. Depression has been linked to increased blood pressure and 46 heart rhythms, as well as chronically elevated stress hormone (应激激素) levels, which can increase the heart's workload. Symptoms of depression include 47 sadness, loss of interest in normal activities, feelings of guilt or hopelessness, tiredness, restlessness and changes in appetite. Some of these 48 may "be discounted by many with heart disease or viewed as a natural part of dealing with aging or heart-health problems", the report indicates. According to Hayes, "It may be natural to grieve and be sad if you have a new diagnosis of heart disease. If those feelings persist or 49 with normal daily functioning, however, heart patients should specifically mention them and be 50 for depression", she advised. A. symptoms B. issue C. jointly D. evaluated E. abnormal F. topic G. separately H. survivors I. consist J. rare K. sustaining L. affects M. interfere N. common O. temporary