单选题 The first line reads; "She sits on the bed with a helpless expression. What is your name? Au-guste. Last name? Auguste. What is your husband" s name? Auguste, I think. " The 32 pages of medical records that follow are the oldest medical description of Alzheimer" s disease. Psychiatrist Konrad Maurer and his colleagues at Johann Wolfgan Goethe University in Frankfurt found the file in their hospital" s archive, where it had been missing for nearly 90 years, and published exerpts from it last May in The Lancet. The notes, in a cramped, archaic German script, were written by Alois Alzheimer—the physician who first described the disease. His patient, Auguste D. , was a 51-year-old woman who had suffered fits of paranoid jealousy and memory lapses so disturbing that her family finally brought her to a local hospital known as the Castle of the Insane. Over the next four years Aizheimer tracked her condition. Upon her death he examined her brain tissue and found the distinctive lesion that are now hallmark of the disease. Today Alzheimer" s afflicts some 4 million Americans. Although it still cannot be cured, or e-ven treated very well, several recent studies hint that some treatments—from estrogen to vitamin E to anti-inflammatory drugs—can reduce either the risk of developing the disorder or its symptoms. And more is being learned about its distinctive pathology. This past year, for instance, researchers discovered a new kind of lesion in Alzheimer" s patients. A genetic study also pinpointed a mutation that is present in some 60 percent of them—a mutation in the DNA of mitochondria, the energy— producing organelles of the cells. But nearly a century ago, it was Alois Alzheimer who first described the disease an in so doing became one of the first physicians to offer a biological basis fro a psychiatric condition. Finding the file, Maurer says, "is like holding history in your hands. "
单选题 Obviously, the discovery of the missing file of Augusted______.
【正确答案】 D
【答案解析】解析:根据文章内容可知,很明显,这项发现将对老年痴呆症的治疗产生重大影响。
单选题 The anatomical characteristics of Alzheimer" s______.
【正确答案】 A
【答案解析】解析:根据文章第二段对丢失文件的描述可知,Alzheimer在患者死后对其大脑组织进行了解剖并发现了现在诊断的老年痴呆症的典型病灶。故选A。
单选题 The findings of the research on Aizheimer"s______.
【正确答案】 A
【答案解析】解析:文章第三段提出,虽然老年痴呆症不能被治愈,但是最近的发现能减少发病率或减轻症状,病理性的研究也取得进展,基因研究也有所发现,这一切都听起来都十分乐观,故选A。
单选题 When he says that finding the file is like holding history in your hands. Maurer means______.
【正确答案】 A
【答案解析】解析:根据文章可知,这份被重新发现的文献完善了老年痴呆症研究历史,为此作者更加确’ 定老年痴呆症的研究历史。
单选题 Which of the following can best be the title for the passage?
【正确答案】 C
【答案解析】解析:本文主要围绕“Auguste D.遗失的文献被重新发现”展开,介绍了这部分文献的主要内容,并引出了老年痴呆症的研究现状,最后又回归这个文献的重要意义。