单选题Young girls at high risk for depression appear to have a malfunctioning reward system in their brains, a new study suggests. The finding comes from research that
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a high-risk group of 13 girls, aged 10 to 14, who were not depressed but had mothers who
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recurrent depression and a low-risk group of 13 girls with no
3
or family history of depression. Both groups were given MRI brain
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while completing a task that could
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either reward or punishment.
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with girls in the low-risk group, those in the high-risk group had
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neural responses during both anticipation and receipt of the reward.
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, the high-risk girls showed no
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in an area of the brain called the dorsal anterior cingulated cortex(背侧前扣带皮质), which is believed to play a role in
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past experiences to assist learning.
The high-risk girls did have greater activation of this brain area
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receiving punishment, compared with the other girls. The researchers said that this suggests that high-risk girls have easier time
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information about loss and punishment than information about reward and pleasure.
"Considered together with reduced activation in the striate(纹状体的)areas commonly observed
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reward, it seems that the reward-processing system is critically
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in daughters who are at elevated risk for depression,
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they have not yet experienced a depressive
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, " wrote Ian H. Gotlib, of Stanford University, and his colleagues. "
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, hmgitudinal studies are needed to determine whether the anomalous activations
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in this study during the processing of
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and losses are associated with the
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onset of depression," they" concluded. The study was published in the April of the Archives of General Psychiatry.
单选题It has been almost half a decade since Norman Mailer described leas Vegas in his novel The American Dream. But it (1) to be one of the most (2) and exhilarating (使人愉快的) holiday destinations in the world. An end-less (3) of colorful sights and activities are surrounded by skyscrapers and the magnificent Nevada desert. With (4) shopping, luxury spas, five-star dining and some of the most extravagant entertainment, you will (5) see, this is a city (6) offers an experience like no other. Perhaps the enduring appeal of this " (7) capital of the world", though, is that it always has something (8) to offer. Recently the Hard Rock Café has been (9) up its act, completing with a new 42 000 sq ft venue, 1 000-seater cinema and an "interactive rock wall"-allowing customers the chance to (10) images of Hard Rock's collection. City Center is an $ 8.5 billion (£5.3 billion) complex on the Strip; a place that, in a city already (11) with extraordinary casinos (娱乐场) and hotels, stands out from the (12) It was the largest privately (13) construction project in the US and has three stand-alone hotels, a sprawling shopping and entertainment district and two 37-storey glass towers of (14) flats, designed by the likes of Norman Foster. Another Las Vegas (15) , Planet Hollywood, has (16) with luxury developers to create Westgate Towers--where you could own a piece of the action and a chance to come back to Las Vegas every year. (17) , the only thing you'll (18) of in Vegas is not knowing which club, restaurant or spa to choose from. But then you can always ask a(n) (19) or the concierge--the fantastic thing about this city is that its residents (20) it as much as you will.
单选题Selection to participate in a top executive-education program is an important rung on the ladder to top corporate jobs. U. S. corporations (1) billions of dollars in this form of management development -- and use it to (2) and train fast-track managers. Yet one (3) of executive education found that less than 5% of the managers (4) to these high-profile programs are women -- and minorities are terribly (5) as well. The numbers are (6) . In regular business (7) usually paid for by the participant, not an employer -- there are plenty of women and minorities. Women, for example, (8) for about 30% of MBA candidates. Yet in the (9) programs paid for by corporations that round out a manager's credentials at a (10) career point, usually at age 40 or 45, companies are making only a (11) investment in developing female and minority executives. A case (12) point: Only about 30% of the 180 executives in Stanford's recent (13) management program were women. Most companies say these days they are (14) hiring and promoting women and minorities-- and there are some (15) trends in overall employment and pay levels so why are companies (16) the ball when it (17) executive education? The schools (18) that they are neither the cause of nor the cure for the problem. A Harvard Business School dean figures that companies are (19) of sending their female executives (20) they don't want to lose them to competitors.
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单选题Conservatism, George Will told me when I interviewed him many years ago, was rooted in reality. It started not from an imagined society but from the world as it actually exists. But conservatives now champion ideas drawn from abstract principles with little regard to the realities of America's present or past. This is a tragedy, because conservatism has an important role to play in modernizing the U. S. Consider the debates over the economy. The Republican prescription is to cut taxes and slash government spending, but what is the evidence that tax cuts are the best path to revive the U. S. economy? Taxes as a percentage of GDP are at their lowest level since 1950. The U. S. is among the lowest taxed of the big industrial economies. So the case that America is grinding to a halt because of high taxation is not based on facts but is simply a theoretical assertion. The rich countries that are in the best shape right now, with strong growth and low unemployment, are ones like Germany and Denmark, neither one characterized by low taxes. In fact, right now any discussion of government involvement in the economy—even to build vital infrastructure—is impossible because it is a cardinal tenet of the new conservatism that such involvement is always and forever bad. Meanwhile, across the globe, from Singapore to South Korea to Germany to Canada, evidence abounds that some strategic actions by the government can act as catalysts for free-market growth. Of course, American history suggests that as well. In the 1950s, '60s and '70s, the U.S. government made massive investments in science and technology, in state universities and in infant industries. Those investments triggered two generations of economic growth and put the U. S. on top of the world of technology and innovation. But that history has been forgotten. When considering health care, for example, Republicans confidently assert that their ideas will lower costs, when we simply do not have much evidence for this. What we do know is that of the world's richest countries, the U.S. has by far the greatest involvement of free markets and the private sector in health care. It also consumes the largest share of GDP, with no significant gains in health on any measurable outcome. We need more market mechanisms to cut medical costs, but Republicans don't bother to study existing health care systems anywhere else in the world. "I know it works in practice," the old saw goes, "but does it work in theory?" Conservatives used to be the ones with heads firmly based in reality. Their reforms were powerful because they used the market, streamlined government and empowered individuals. We need conservative ideas to modernize the U. S. economy and reform American government. But what we have instead are policies that don't reform but just cut and starve government—a strategy that pays little attention to history or best practices from around the world and is based instead on a theory.
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Healthy soda? That may strike some as
an oxymoron. But for Coca-Cola and PepsiCo. it's a marketing
opportunity. In coming months, both companies will introduce new
carbonated drinks that are fortified with vitamins and minerals: Diet Coke Plus
and Tava, which is PepsiCo's new offering. They will be promoted as "sparkling
beverages." The companies are not tailing them soft drinks because people are
turning away from traditional soda, which has been hurt in part by publicity
about its link to obesity. While the soda business remains a $68
billion industry in the United States, consumers are increasingly reaching for
bottled water, sparkling juices and green tea drinks. Irr'2005. the mount of
soda sold in this country dropped for the first time in recent history. Even the
diet soda business has slowed. Coca-Cola's chief executive. E.
Neville Isdell. clearly frustrated that his industry has been singled out in the
obesity debate, insisted at a recent conference that his diet products should be
included in the health and wellness category because, with few or no calories,
they are a logical answer m expanding waistlines. "Diet and
light brands are actually health and wellness brands," Mr. Isdell said. He
asserted that Diet Coke Plus was a way to broaden the category to attact new
consumers. Tom Pirko. president of Bevmark, a food and beverage
consulting firm, said it was "a joke" to market artificially sweetened soft
drinks as healthy, even if they were fortified with vitamins and minerals.
Research by his firm and others shows that consumers think of diet soft drinks
as "the antithesis of healthy," he said. These consumers "comment on
putting something synthetic and not natural into their bodies when they consume
diet colas," Mr. Pirko said. "And in the midst of a health and welfare boom,
that ain't good." The idea of healthy soda is not entirely new.
In 2004, Cadbury Schweppes caused a stir when it unveiled 7Up Plus, a
low-calorie soda fortified with vitamins and minerals. Last year, Cadbury tried
to extend the healthy halo over its regular 7Up brand by labeling it "100
percent natural." But the company changed the label to "100 percent natural
flavor" after complaints from a nutrition group that a product containing
high-fructose com syrup should not be considered natural, and 7Up Plus has
floundered. The new fortified soft drinks earned grudging approval
from Michael F. Jacobsen, executive director of the Center for Science in the
Public Interest. a nutrition advocacy group and frequent critic of regular soft
drinks, which it has labeled "liquid candy." A survey by Morgan
Stanley found that only 10 percent of consumers interviewed in 2006 considered
diet colas a healthy choice, compared with 14 percent in 2003. Furthermore, 30
percent of the consumers who were interviewed last year said that they were
reluctant to drink beverages with artificial sweeteners, up from 21 percent in
2004.
单选题Two years ago, Rupert Murdoch"s daughter, Elisabeth, spoke of the "unsettling dearth of integrity across so many of our institutions". Integrity had collapsed, she argued, because of a collective acceptance that the only "sorting mechanism" in society should be profit and the market. But "it"s us, human beings, we the people who create the society we want, not profit".
Driving her point home, she continued: "It"s increasingly apparent that the absence of purpose, of a moral language within government, media or business could become one of the most dangerous goals for capitalism and freedom." This same absence of moral purpose was wounding companies such as News International, she thought, making it more likely that it would lose its way as it had with widespread illegal telephone hacking.
As the hacking trial concludes—finding guilty one ex-editor of the
News of the World
, Andy Coulson, for conspiring to hack phones, and finding his predecessor, Rebekah Brooks, innocent of the same charge—the wider issue of dearth of integrity still stands. Journalists are known to have hacked the phones of up to 5,500 people. This is hacking on an industrial scale, as was acknowledged by Glenn Mulcaire, the man hired by the
News of the World
in 2001 to be the point person for phone hacking. Others await trial. This long story still unfolds.
In many respects, the dearth of moral purpose frames not only the fact of such widespread phone hacking but the terms on which the trial took place. One of the astonishing revelations was how little Rebekah Brooks knew of what went on in her newsroom, how little she thought to ask and the fact that she never inquired how the stories arrived. The core of her successful defence was that she knew nothing.
In today"s world, it has become normal that well-paid executives should not be accountable for what happens in the organisations that they run. Perhaps we should not be so surprised. For a generation, the collective doctrine has been that the sorting mechanism of society should be profit. The words that have mattered are efficiency, flexibility, shareholder value, business-friendly, wealth generation, sales, impact and, in newspapers, circulation. Words degraded to the margin have been justice, fairness, tolerance, proportionality and accountability.
The purpose of editing the
News of the World
was not to promote reader understanding, to be fair in what was written or to betray any common humanity. It was to ruin lives in the quest for circulation and impact. Ms Brooks may or may not have had suspicions about how her journalists got their stories, but she asked no questions, gave no instruction—nor received traceable, recorded answers.
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Any normal species would be delighted
at the prospect of cloning. No more nasty surprises like sickle cell or Down
syndrome--just batch after batch of high-grade and, genetically speaking,
immortal offspring! But representatives of the human species are responding as
if someone had proposed adding Satanism to the grade-school Curriculum.
Suddenly, perfectly secular folks are throwing around words like sanctity and
retrieving medieval-era arguments against the pride of science. No one has
proposed burning him at the stake, but the poor fellow who induced a human
embryo to double itself has virtually recanted proclaiming his reverence for
human life in a voice, this magazine reported," choking with emotion."
There is an element of hypocrisy to much of the anti-cloning furor, or if
not hypocrisy, superstition. The fact is we are already well down the path
leading to genetic manipulation of the creepiest sort. Life-forms can be
patented, which means they can be bought and sold and potentially traded on the
commodities markets. Human embryos are life-forms, and there is nothing to stop
anyone from marketing them now, on the same shelf with the Cabbage Patch
dolls. In fact, any culture that encourages in vitro
fertilization has no right to complain about a market in embryos. The assumption
behind the in vitro industry is that some people's genetic material is worth
more than others' and deserves to be reproduced at any expense. Millions of
low-income babies die every year from preventable ills like dysentery, while
heroic efforts go into maintaining yuppie zygotes in test tubes at the
unicellular stage. This is the dread "nightmare” of eugenics in familiar,
marketplace form which involves breeding the best-paid instead of the best.
Cloning technology is an almost inevitable byproduct of in vitro fertilization.
Once you decide to go to the trouble of in vitro, with its potentially hazardous
megadoses of hormones for the female partner and various indignities for the
male, you might as well make a few backup copies of any viable embryo that's
produced. And once you've got the backup organ copies, why not keep a few in the
freezer, in case Junior ever needs a new kidney or cornea? The
critics of cloning say we should know what we're getting into, with all its
Orwellian implications. But if we decide to outlaw cloning, we should understand
the implications of that. We would be saying in effect that we prefer to leave
genetic destiny to the crap shooting of nature, despite sickle-cell anemia and
Tay-Sachs and all the rest, because ultimately we don't trust the market to
regulate life itself. And this may be the hardest thing of all to
acknowledge: that it isn't so much 21st century technology we fear, as what will
happen to that technology in the hands of old-fashioned 20th century
capitalism.
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On September 30th students at the
University of Massachusetts threw a toga (a ceremonial gown) party. The cops
showed up, uninvited. They charged the host, James Connolly, with underage
drinking, making too much noise, and having a keg without a licence. For
punishment, he had to put on his toga again and stand in front of the police
station for an hour. Dan Markel of Florida State University
reckons that such "shaming punishments" are on the rise. In 2003 a couple of
teenagers who defaced a nativity scene in Ohio had to parade through town with a
donkey. "The punishment must fit the crime," explained the
judge, Michael Cicconetti. Several cities have aired the names of men caught
soliciting prostitutes on "John TV". In 2004, a federal appeals court agreed
that a mail thief could be made to stand outside a California post office
wearing a sandwich board. "I stole mail," it read. "This is my punishment." In
Virginia, if you fail to pay child support, you may find your car wheel-clamped:
pink if you are neglecting a girl, blue for a boy. Many support
shaming punishments. Amitai Etzioni of George Washington University has argued
that they are a good way to express communal values. Fines, in contrast, imply
that you can buy a clear conscience. And shame seems to be a powerful deterrent.
Mr Cicconetti says he sees few repeat offenders. Cheerful Hobbesian types want
everyone to know who the bad guys are, so that decent citizens can avoid
them. Others are doubtful. According to Mr Markel, shaming
punishments undermine human dignity. He suggests alternative punishments that
omit the public-humiliation factor. A landlord who flouts the health code, for
example, could be made to stay in one of his own slums. And it is true that
there is something unpleasant about the desire to see other people humiliated.
Remember the matron who objects to Hester Prynne's scarlet letter: "Why, look
you, she may cover it with a brooch, or suchlike heathenish adornment, and so
walk the streets as brave as ever!" But voters appear to be
comfortable on the high horse. Ted Poe, a former district judge from Texas, made
his reputation by issuing a string of embarrassing sentences. He called this
"Poetic justice." Once, he sentenced a man who stole pistols from the Lone
Ranger to shovel manure in the Houston police stables. In 2004 Mr Poe was
elected to the House of Representatives at his first
attempt.
单选题Erroneous virtues are running out of control in our culture. I don't know how many times my 13-year-old son has told me about classmates who received $10 for each "A" grade on their report cards—hinting that I should do the same for him should he ever receive an A. Whenever he approaches me on this subject, I give him the same reply: forget it! This is not to say that I would never praise my son for doing well in school. But my praise is not meant to reward or elicit future achievements, but rather to express my genuine delight in the satisfaction he feels at having done his best. Doling out $10 sends out the message that the feeling alone isn't good enough. As a society, we seem to be on the brink of losing our internal control—the ethical boundaries that guide our actions and feelings. Instead, these ethical standards have been eclipsed by external "stuff" as a measure of our worth. We pass this obscene message on to our children. We offer them money for learning how to convert fractions to decimals. Refreshments are given as a reward for reading. In fact, in one national reading program, a party awaits the entire class if each child reads a certain number of books within a four-month period. We call these things incentives, telling ourselves that if we can just reel them in and get them hooked, then the internal rewards will follow. I recently saw a television program where unmarried, teenage mothers were featured as the participants in a program that offers a $10 a week "incentive" if these young women don't get pregnant again. Isn't the daily plight of being a single, teenaged mother enough to discourage them from becoming pregnant again? No, it isn't, because we as a society won't allow it to be. Nothing is permitted to succeed or fail on its own merits anymore. A staple diet of candy bars makes an ordinary apple or orange seem sour. Similarly, an endless parade of incentives corrodes our ability to feel a genuine sense of inner peace (or inner conflict). The simple virtues of honesty, kindness and integrity suffer from an image problem and are in desperate need of better publicity. One way to do this is by example. I fear that in our so-called upwardly mobile world we are on a downward spiral towards becoming morally bankrupt. We may soon render ourselves worthless inside, while desperately clinging to a shell of appearances.
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Genghis Khan was not one to agonize
over gender roles. He was into sex and power, and he didn't mind saying so. "The
greatest joy a man can know is to conquer his enemies and drive them before
him." The emperor once thundered. Genghis Khan conquered two thirds of the known
world during the early 13th century and he may have set an all-time record for
what biologists call reproductive success. An account written 33 years after his
death credited him with 20,000 descendants. Men's manners have
improved markedly since Genghis Khan's day. At heart, though, we're the same
animals we were 800 years ago, which is to say we are status seekers. We may
talk of equality and fraternity. We may strive for classless societies. But we
go right on building hierarchies, and jockeying for status within them. Can we
abandon the tendency? Probably not. As scientists are now discovering, status
seeking is not just a habit or a cultural tradition. It's a design feature of
the male psyche--a biological drive that is rooted in the nervous system and
regulated by hormones and brain chemicals. How do we know this
relentless one-upmanship is a biological endowment? Anthropologists find the
same pattern virtually everywhere they 10ok and so do zoologists. Male
competition is fierce among crickets, crayfish and elephants, and it's
ubiquitous among higher primates, for example, male chimpanzees have an
extraordinarily strong drive for dominance. Coincidence?
Evolutionists don't think so. From their perspective, life is essentially
a race to repro-duke, and natural selection is bound to favor different
strategies in different organisms. In reproductive terms, they have vastly more
to gain from it. A female can't flood the gene pool by commandeering extra
mates; no matter how much sperm she attracts, she is unlikely to produce more
than a dozen viable offspring. But as Genghis Khan's exploits make clear, males
can profit enormously by out mating their peers. It's not hard to see how that
dynamic, played out over millions of years, would leave modern men fretting over
status. We're built from the genes that the most determined competitors passed
down. Fortunately, we don't aspire to families of 800. As
monogamy and contraceptives may have leveled the reproductive playfield, power
has become its own psychological reward. Those who achieve high status still
enjoy more sex with more partners than the rest of us, and the reason is no
mystery. Researchers have consistently found that women favor signs of "earning
capacity" over good looks. For sheer sex appeal, a doughy (脸色苍白的) bald guy in a
Rolex will outscore a stud (非常英俊的男子) in a Burger King uniform almost every
time.
单选题People in the United States in the nineteenth century were haunted by the prospect that unprecedented change in the nation's economy would bring social chaos. In the years following 1820, after several decades of relative stability, the economy entered a periodof sustained and extremely rapid growth that continued to the end of the nineteenth century. Accompanying that growth was a structural change that featured increasing economic diversification and a gradual shift in the nation's labor force from agriculture to manufacturing and other nonagricultura pursuits Although the birth rate continued to, decline from its high level of the eighteenth and early nineteenth centuries, the population roughly doubled every generation during the rest of the nineteenth century. As the population grew, its makeup also changed. Massive waves of immigration brought new ethnic groups into the country. Geographic and social mobility -- downward as well as upward -- touched almost everyone. Local studies indicate that nearly three- quarters of the population in the North and South, in the emerging cities of the Northeast, and in the restless rural counties of the West changed their residence each decade. As a consequence, historian David Donald has written, "Social atomization affected every segment of society", and it seemed to many people that "all the recognized values of orderly civilization were gradually being eroded." Rapid industrialization and increased geographic mobility in the nineteenth century had special implications for women because these changes tended to magnify social distinctions. As the roles men and women played in society became more rigidly defined, so did the roles they played in the home. In the context of extreme competitiveness and dizzying social change, the household lost many of its earlier functions and the home came to serve as a haven of tranquillity and order. As the size of families decreased, the roles of husband and wife became more clearly differentiated than ever before. In the middle class especially, men participated in the productive economy while women ruled the home and served as the custodians of civility and culture. The intimacy of marriage that was common in earlier periods was rent, and a gulf that at times seemed unbridgeable was created between husbands and wives.
单选题While more and more Americans expand their wardrobes (衣柜) with the click of a mouse, the Japanese are a step ahead, buying clothes on their cell-phones. It"s almost exactly the same as shopping on a computer, just smaller and more mobile. In Japan, cell-phone commerce is an $83 billion industry. The leader is Xavel, which launched girls walker, com the first free-of-charge cell-phone consumer entrance. Six years later, it"s the country"s most popular cell-phone, shopping site getting 100 million hits a day. Its partner, girls auction, com boasts 1.5 million members and $43 million monthly cell-phone transactions. "If I was going to do business, I was going to do it with women in their 20s and 30s," says the CEO. "I wondered why nobody thought of it, considering they are such a huge market."
Another thing nobody thought of was a buy-it-as-you-see-it fashion show. In August, Xavel threw Japan"s largest fashion event to date, the Tokyo Girls Collection. (1)The 12,600 attendees and 15 million people watching the live cell-phone broadcast could purchase items on their phones as soon as they appeared on the catwalk. Shin Akamatsu launched his Joias line at the festival and received more orders than the established labels did. "We struck gold right from the beginning," says the creative director, who saw $4.2 million in sales in five months. Other brands plan to present new lines at the next event.
Also catching on is Japan"s Rakuten. Cell-phone sales account for 34% of its transactions. "Cell-phone companies realized the potential, so we too started taking Cell-phone commerce seriously," says spokeswoman Kuniko Narita. "Our turnover (营业额) increased greatly." The Japanese aren"t just shopping on cell phones but also with them. A new "wallet cell-phone" functions as a credit or ID card. The handset has a computer chip similar to that found in electronic key cards. (2)Japanese girls are buying mascara (睫毛膏), mints and magazines at convenience stores simply by swiping their phones past a scanner near the cash register. So what"s next? "People have star ted buying big things," says Narita. "You can even buy a helicopter or a $ 3.2 million jewel on a cell phone."
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单选题"What's the difference between God and Larry Ellison?" asks an old software industry joke. Answer: God doesn't think he's Larry Ellison. The boss of Oracle is hardly alone among corporate chiefs in having a reputation for being rather keen on himself. Indeed, until the bubble burst and the public turned nasty at the start of the decade, the cult of the celebrity chief executive seemed to demand bossly narcissism, as evidence that a firm was being led by an all-conquering hero. Narcissus in Greek myth met a nasty end, of course. And in recent years, boss-worship has come to be seen as bad for business. In his management besteller, Good to Great, Jim Collins argued that the truly successful bosses were not the self-proclaimed stars who adorn the covers of Forbes and Fortune, but instead self-effacing, thoughtful, monkish sorts who lead by inspiring example. A statistical answer may be at hand. For the first time, a new study, "It's All About Me", to be presented next week at the annual gathering of the American Academy of Management, offers a systematic, empirical analysis of what effect narcissistic bosses have on the firms they run. The authors, Arijit Chatterjee and Donald Hambriek, of Pennsylvania State University, examined narcissism in the upper echelons of 105 firms in the computer, and software industries. To do this, they had to solve a practical problem: studies of narcissism have hitherto relied on surveying individuals personally, something for which few chief executives are likely to have time or inclination. So the authors devised an index of narcissism using six publicly available indicators obtainable without the co-operation of the boss. These are: the prominence of the boss's photo in the annual report; his prominence in company press releases; the length of his "Who's Who" entry; the frequency of his use of the first person singular in interviews; and the ratios of his cash and non-cash compensation to those of the firm's second-highest paid executive. Narcissism naturally drives people to seek positions of power and influence, and because great self-esteem helps your professional advance, say the authors, chief executives will tend on average to be more narcissistic than the general population. How does that affect a firm? Messrs Chatterjee and Hambrick found that highly narcissistic bosses tended to make bigger changes in the use of important resources, such as research and development, or in spending and leverage; they carried out more and bigger mergers and acquisitions; and their results were both more extreme (more big wins or big losses) and more volatile than those of firms run by their humbler peers. For shareholders, that could be good or bad.