单选题After years of defensiveness, a siege mentality and the stonewalling of any criticism, a quiet revolution is under way in animal research.
What has triggered this change of heart? It"s partly down to the economic climate plus fewer new medicines and the removal of much of the threat from animal rights extremism, in the UK at least.
Until recently the only criticism of animal research came from antivivisection groups who persistently complained about a lack of transparency. Now criticism is coming from researchers too, with the recognition that not all aspects of animal experimentation are as robust as they should be and that something needs to change.
That is why we have published new guidelines aimed at improving the quality of reporting on animal experiments in research papers. These have been met with support, notably from the major funding bodies and many international journals. This is indicative of the new climate in which we operate.
Five years ago the guidelines would have been met with scepticism and accusations of increased bureaucracy from some within the scientific community.
The difference is that these guidelines come in the wake of recent studies, which reveal serious shortcomings in animal research. One by my own organization, the UK"S NC3Rs, found that key information was missing from many of the 300 or so publications we analysed that described publicly funded experiments on rodents and monkeys in the UK and the US.
The new guidelines should ensure the science emerging from animal research is maximised and that every animal used counts. Better reporting will allow greater opportunity to evaluate which animal models are useful and which are not. One way of doing this is through the systematic reviews that are the gold standard in clinical studies but rarely undertaken for animal studies due to the lack of information published.
Animal research has been a thorn in the side of researchers for many years. We can"t afford to get this wrong, scientifically, ethically or financially. Failings in reporting animal data properly can be perceived as an attempt to hide something, either about the quality or value of what is being done. When animal research is funded from the public purse a public mandate is essential. There is much scope for improvement. It is time for scientists—funders, researchers and editors—to use the new guidelines to put our house in order.
单选题A healthy life is frequently thought to be ______ with the open countryside and homegrown food.
单选题But the depth of a novel and the value of its artistic and ideological feature do not depend on the theme-either______or significant
单选题______, the market will have to overcome some of the highest hurdles. It's seen in a long time.
单选题Many drama critics (considered) Richard Burton's interpretation of Hamlet superior (than) Sir Lawrence Olivier's version (produced) several years (earlier).
单选题The author thinks that Danes adopt a______ attitude towards their country.
单选题Artificial intelligence deals partly with the______between the computer and the human brain. A. profile B. mighty C. analogy D. leakage
单选题The human ear contains the organ for hearing and the organ for balance. Both organs involve fluid-filled channels containing hair cells that produce electrochemical impulses when the hairs are stimulated by moving fluid. The ear can be divided into three regions: outer, middle, and inner. The outer ear collects sound waves and directs them to the eardrum separating the outer ear from the middle ear. The middle ear conducts sound vibrations through three small bones to the inner ear. The inner ear is a network of channels containing fluid that moves in response to sound or movement. To perform the function of hearing, the ear converts the energy of pressure waves moving through the air into nerve impulses that me brain perceives as sound. Vibrating objects, such as the vocal cords of a speaking person, create waves in me surrounding air. These waves cause the eardrum to vibrate with the same frequency. The three bones of the middle ear amplify and transmit the vibrations to the oval window, a membrane on the surface of the cochlea, the organ of hearing. Vibrations of me oval window produce pressure waves in the fluid inside me cochlea. Hair cells in the cochlea convert the energy of the vibrating fluid into impulses that travel along the auditory nerve to the brain. The organ for balance is also located in the inner ear. Sensations related to body position are generated much like sensations of sound. Hair cells in the inner ear respond to changes in head position with respect to gravity and movement. Gravity is always pulling down on the hairs, sending a constant series of impulses to the brain. When the position of the head changes—as when the head bends forward—the force on the hair cells changes its output of nerve impulses. The brain then interprets these changes to determine the head's new position.
单选题During the period of economic recession, daily necessities were in short supply and had to be ______.
单选题Battles are like marriages. They have a certain fundamental experience they share in common; they differ infinitely, but still they are all alike. A battle seems to me a conflict of will with death in the same way that a marriage of love is the identification of two human beings to the end of creation of life--as death is the reverse of life, and love of hate. Battles are commitments to cause death as marriages are commitments to create life. Whether, for any individual, either union results in death or in the creation of life, each risks it--and in the risk commits himself. As the servants of death, battles will always remain horrible. Those who are fascinated by them are being fascinated by death. There is no battle aim worthy of the name except that of ending all battles. Any other conception is, literally, suicidal. The fascist worship of battle is a suicidal drive; it is love of death instead of life. In the same idiom, to triumph in battle over the forces which are fighting for death is-- again literally--to triumph over death. It is a surgeon's triumph as he cuts a body and bloodies his hands in removing a cancer in order to triumph over death that is in the body. In these thoughts I have found my own peace, and I return to an army that fights death and cynicism in the name of life and hope. It is a good army. Believe in it.
单选题Sometimes you have to make a ______to get what you want.
单选题__________ you find yourself in a condition of being troubled or worried about some trifles, please cultivate a hobby.
单选题He always studies the______in the paper as he wants to find a good second- hand car.
单选题Standard English is the variety of English which is usually used in print and winch is normally taught in schools and to non-native speakers leaning the language. It is also the variety which is normally (71) by educated people and used in news broadcasts and other (72) situations. The difference between standard and nonstandard, it should be noted, has (73) in principle to do with differences between formal and colloquial (74) ; standard English has colloquial as well as formal variants. (75) , the standard variety of English is based on the London (76) of English that developed after the Norman Conquest resulted in the removal of the Court from Winchester to London. This dialect became the one (77) by the educated, and it was developed and promoted (78) a model, or norm, for wider and wider segments of society. It was also the (79) that was carried overseas, but not one unaffected by such export. Today, (80) English is arranged to the extent that the grammar and vocabulary of English are (81) the same everywhere in the world where English is used; (82) among local standards is really quite minor, (83) the Singapore, South Africa, and Irish varieties have very (84) difference from one another so far as grammar and vocabulary are (85) . Indeed, Standard English is so powerful that it exerts a tremendous (86) on all local varieties, to the extent that many long-established dialects of England have (87) much of their vigor and there is considerable pressure on them to be (88) . This latter situation is not unique (89) English: it is also true in other countries where processes of standardization are (90) . But it sometimes creates problems for speakers who try to strike some kind of compromise between local norms and national, even supranational (跨国的) ones.
单选题She was so ______ in her work that she didn"t notice me when I came in the room.
单选题The drug store at the corner of our street sells aspirins and ______ penicillin prescriptions.
单选题It can be inferred that the author of the passage expects that the experience of the student mentioned as having studied Wife in the Right would have one of the following effects. That is ______.
单选题Planning is a very important activity in our lives yet really sophisticated. It can give pleasure, even excitement, 【C1】______cause quite severe headaches. The more significant the task【C2】______is, the more careful the planning requires. Getting to school or to work on time is a task requiring【C3】______or no planning, and it is almost a【C4】______. Meanwhile when you luckily to enjoy a month's touring holiday【C5】______, or better【C6】______, getting married, it would a different matter altogether. It' the【C7】______involves a church wedding, with fifty guests, a reception, a honeymoon in Venice, and【C8】______to a new home, this requires even more planning to make【C9】______that it is successful. Planning is our way of trying to ensure success and【C10】______avoiding costly failures we cannot afford. It is【C11】______essential and fundamental to mankind as a【C12】______, to individual nations, to families and single people; the【C13】______may vary, but the【C14】______of importance does not. In essence, a nation planning its resources and【C15】______does not differ from the【C16】______weekly shopping or monthly household budget.【C17】______are designed to ensure an adequate supply of essentials,【C18】______a rate of spending within the limits of【C19】______, and if properly carried out, will【C10】______shortages, wastage and over-expenditure.
单选题This platform would collapse if all of us ______ on it.
单选题Now the ______ port city near the mouth of the mighty Yangtze River is hoping to leave its record of turmoil behind and renew its status as the epicenter of Chinese modernization.
