摘要
目的:分析沈阳市城区居民结直肠癌的发病和死亡数据及其变化趋势,为结直肠癌防控提供科学依据。方法:分析2011—2017年沈阳市城区居民结直肠癌的发病和死亡数据,计算粗发病率和粗死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、累积率、截缩率以及年度变化百分比(annual percent change,APC)。结果:2011—2017年沈阳市城区居民结直肠癌发病13801例,粗发病率为52.48/10万,中标率为25.52/10万,世标率为25.36/10万,粗发病率APC为5.89%(P<0.05)。其中,结肠癌粗发病率为27.12/10万,APC为7.52%(P<0.05);直肠癌粗发病率为25.37/10万,APC为4.19%(P<0.05)。结直肠癌死亡6687例,粗死亡率为25.43/10万,中标率为11.85/10万,世标率为11.63/10万,粗死亡率APC为16.35%(P<0.05)。从性别分布来看,男性结直肠癌的粗发病率和粗死亡率均高于女性。发病和死亡年龄高峰均为80岁左右。结论:沈阳市城区居民结直肠癌发病率和死亡率均呈现上升趋势,且结肠癌的上升趋势更加明显。应将男性结直肠癌高危人群作为重点关注对象,加强对健康生活方式的宣传,并对结肠癌危险因素进行有效干预,同时加强结直肠癌高年龄组的筛查工作,进一步完善结直肠癌防治措施。
Objective:The aim of this study was to analyze the incidence rates and mortality rates as well as their trends in colorectal cancer in residents of Shenyang urban area from 2011 to 2017,and provide the basis for the prevention and control of colorectal cancer.Methods:The incidence and mortality data of colorectal cancer of Shenyang residents in urban area from 2011 to 2017 was analyzed.The crude incidence rate,the crude mortality rate,age-standardized incidence rate by Chinese standard population,age-standardized incidence rate by world standard population,cumulative rate,truncated rate and annual percent change(APC)were calculated.Results:From 2011 to 2017,13801 new cases of colorectal cancer in Shenyang urban area were registered.The crude incidence rate of colorectal cancer in Shenyang urban area was 52.48 per 100000;the age-standardized incidence rate by Chinese standard population was 25.52 per 100000;the age-standardized incidence rate by world standard population was 25.36 per 100000;the APC of crude incidence was 5.89%(P<0.05).The crude incidence rate of colon cancer was 27.12 per 100000 and the APC of crude incidence was 7.52%(P<0.05),whereas the crude incidence rate of rectal cancer was 25.37 per 100000 and the APC of crude incidence was 4.19%(P<0.05).Total of 6687 death cases of colorectal cancer were registered from 2011 to 2017.The crude mortality rate of colorectal cancer was 25.43 per 100000;the age-standardized mortality rate by Chinese standard population was 11.85 per 100000;the age-standardized mortality rate by world standard population was 11.63 per 100000;the APC of crude mortality was 16.35%(P<0.05).According to gender distribution,both the incidence rate and the mortality rate of males were higher than those of the females.The peak of incidence rate and mortality rate occurred in the 80s age group.Conclusion:The trends of incidence rate and mortality rate of colorectal cancer in residents of Shenyang urban area were both ascending,and this trend was more obvious in colon cancer.It is necessary to focus on high-risk population of colorectal cancer in men,strengthen healthy lifestyle promotion and take effective intervention on risk factors of colon cancer as well as increase the screening of colorectal cancer in high-age group and improve the prevention and treatment methods of colorectal cancer.
作者
聂慧芳
孙百军
吕艺
NIE Huifang;SUN Baijun;LÜYi(Department of Chronic Disease Control and Prevention,Shenyang Center for Disease Control and Prevention,Shenyang 110031,Liaoning Province,China)
出处
《肿瘤》
CAS
CSCD
北大核心
2022年第7期499-507,共9页
Tumor
关键词
结直肠肿瘤
发病
死亡率
趋势分析
Colorectal neoplasms
Incidence
Mortality
Trend analysis
