摘要
目的:探讨沙丁胺醇联合布地奈德对哮喘急性发作患儿肺功能的影响。方法:选择2017年5月—2019年3月我院收治的100例哮喘急性发作患儿作为研究对象,按随机数字表法分为对照组与观察组,各50例。对照组实施常规治疗,观察组在此基础上给予布地奈德(0.5 mg,tid)治疗。比较两组治疗效果及肺功能。结果:治疗后,观察组治疗总有效率高于对照组,用力肺活量(FVC)、最大呼气流量(PEF)、用力肺活量与第1秒末用力呼气容积比值(FEV1/FVC)均高于对照组,差异有统计学意义(P<0.05)。结论:沙丁胺醇联合布地奈德治疗哮喘急性发作患儿的疗效显著,利于提高患儿肺功能。
Objective:To investigate the effect of salbutamol combined with budesonide on lung functions in children with acute asthma attack.Methods:100 children with acute asthma attack admitted to our hospital from May 2017 to March 2019 were selected as subjects investigated,and they were randomly divided into a control group and an observation group,50 cases each.The children in the control group received conventional treatment,and the children in the observation group were given budesonide(0.5 mg,tid)on the basis of the treatment in the control group.The therapeutic effect and lung functions were compared between the two groups.Results:After treatment,the total effective rate in the observation group was higher than that in the control group,and the forced vital capacity(FVC),peak expiratory flow(PEF)and the ratio of forced expiratory volume at the end of the first second to forced vital capacity(FEV1/FVC)were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion:Salbutamol combined with budesonide is significantly effective in the treatment of acute asthma attack in children,which is beneficial to the improvement of lung functions in the children.
作者
李越
刘东英
Li Yue;Liu Dong-ying(Department of Emergency,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou Henan 450052,China;Henan Cancer Hospital,Zhengzhou Henan 450052,China)
出处
《中国合理用药探索》
CAS
2019年第10期102-103,107,共3页
Chinese Journal of Rational Drug Use
