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低剂量SPECT/CT对甲状腺良恶性结节鉴别的增益价值 被引量:5

Gain value of low-dose SPECT/CT in differential diagnosis of benign and malignant thyroid nodules
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摘要 目的评价低剂量SPECT/CT在鉴别甲状腺良恶性结节中的增益价值。方法收集触诊/彩色多普勒超声考虑甲状腺结节患者41例,分别行^(99)Tc^(m)O_(4)-平面显像和低剂量SPECT/CT融合显像,以病理结果为金标准,比较2者诊断效能。结果低剂量SPECT/CT融合显像诊断甲状腺结节良恶性的灵敏度、特异度、准确率及受试者工作特征(ROC)曲线下面积(AUC)分别为61.90%、53.33%、63.41%和0.64;均高于^(99)Tc^(m)O_(4)-平面显像的19.05%、45.00%、31.70%和0.32(P均<0.05)。结论低剂量SPECT/CT对恶性甲状腺结节的诊断效能优于^(99)Tc^(m)O_(4)-平面显像。 Objective To evaluate the gain value of low-dose SPECT/CT in differential diagnosis of benign and malignant thyroid nodules.Methods Totally 41 patients with thyroid nodule considered by palpation/color Doppler ultrasonography were prospectively collected.^(99)Tc^(m)O_(4)-plane imaging,low-dose SPECT/CT fusion imaging were performed,respectively.Results The sensitivity,specificity,accuracy and area under the receiver operating characteristic(ROC)curve(AUC)of low-dose SPECT/CT fusion imaging in differential diagnosis of benign and malignant thyroid nodules were 61.90%,53.33%,63.41%and 0.64,respectively;which were higher than those of planar imaging of 19.05%,45.00%,31.70%and 0.32(all P<0.05).Conclusion Low-dose SPECT/CT is better than^(99)Tc^(m)O_(4)-planar imaging in diagnosis of malignant thyroid nodule.
作者 牛静 刘海燕 刘静 武志芳 李思进 NIU Jing;LIU Haiyan;LIU Jing;WU Zhifang;LI Sijin(Department of Nuclear Medicine,the First Hospital of Shanxi Medical University,Taiyuan030001,China;Collaborative Innovation Center for Molecular Imaging,Taiyuan030001,China;Department of General Surgery,the First Hospital of Shanxi Medical University,Taiyuan030001,China)
出处 《中国医学影像技术》 CSCD 北大核心 2020年第S01期16-19,共4页 Chinese Journal of Medical Imaging Technology
基金 山西省科技成果转化引导专项项目(201804D131042) 山西省高等学校科技创新项目(20141101) 山西省卫生和计划生育委员会科研课题(2015036)
关键词 甲状腺结节 体层摄影术 发射型计算机 单光子 体层摄影术 X线计算机 thyroid nodule tomography,emission-computed,single-photon tomography,X-ray computed
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