摘要
富含血小板血浆(Platelet-rich plasma,PRP)是自患者全血中分离制备的浓缩血小板血浆,富含各种生长因子,在皮肤科领域的应用日渐扩展,可单独或联合应用于包括面部年轻化、黄褐斑等在内的多种皮肤疾病。黄褐斑作为一种复杂的面部获得性色素增加性皮肤病,发病率高且难以治愈,极易反复,给广大患者造成极大困扰。近年来国内外关于PRP在黄褐斑中的应用研究报道正日益增多,主要为单用或联合其它黄褐斑治疗方法的临床研究,绝大部分提示PRP对于黄褐斑的治疗有较好的应用前景;仅有少数潜在治疗机制研究,有待进一步探索。
Platelet-rich plasma(PRP)is a concentrated platelet plasma prepared from the whole blood of patients,which is rich in various growth factors.It is increasingly used alone or in combination for various skin diseases,including facial rejuvenation and melasma.As a complex facial acquired pigment increase skin disease,melasma has a high incidence and is challenging to cure.Moreover,it is elementary to recur,causing great distress to most patients.In recent years,there have been more and more domestic and foreign research reports on the application of PRP in melasma,mainly clinical studies on single or combined with other melasma treatment methods.Most of them suggest that PRP has a good application prospect for melasma treatment.However,only a few studies on potential treatment mechanisms were performed and needed to be further explored.Therefore,this paper mainly reviews the clinical and mechanistic studies on the application of PRP in melasma in recent years.
作者
高嘉雯
王秀丽
GAO Jiawen;WANG Xiuli(Institute of Photomedicine,Shanghai Skin Disease Hospital,Tongji University School of Medicine,Shanghai 200443,China)
出处
《皮肤科学通报》
2022年第5期441-445,共5页
Dermatology Bulletin
