摘要
目的探讨中西医结合治疗宫腔粘连(IUA)引起的复发性流产(RSA)患者的临床效果。方法选取2013年2月至2019年3月广西壮族自治区妇幼保健院收治的IUA引起的70例RSA患者作为研究对象,依照随机数字表法分为观察组与对照组,各35例。两组均行宫腔镜下粘连分离术,对照组给予黄体酮胶囊+戊酸雌二醇片治疗,观察组在对照组基础上给予独特中医药方治疗。比较两组疗效、治疗前后中医证候积分、术后月经量恢复率、妊娠结局(妊娠率以及妊娠6周、妊娠12周自然流产率)。结果观察组治疗有效率为94.29%(33/35),高于对照组77.43%(25/35)(P<0.05);治疗后观察组中医证候积分低于对照组(P<0.05);观察组术后1个月、术后2个月、术后3个月的月经量恢复率高于对照组(P<0.05);观察组术后3个月宫腔镜下子宫恢复情况优于对照组(P<0.05);观察组妊娠6周、妊娠12周自然流产率均低于对照组(P<0.05)。结论中西医结合治疗IUA引起的RSA效果显著优于单纯西医治疗。
Objective To explore the effects of the integrated traditional Chinese and Western Medicine on recurrent miscarriage(RSA)caused by intrauterine adhesions(IUA).Methods A total of 70 cases of RSA caused by IUA were selected in Guangxi Zhuang Autonomous Region Maternal and Child Health Hospital from February 2013 to March 2019.According to the random number table method,they were divided into observation group(35 cases)and control group(35 cases).Both groups underwent hysteroscopic mucosal separation,and the control group was given progesterone capsules and estradiol valerate,and the observation group was given a unique Chinese medicine prescription based on the control group.Compare the efficacy of the 2 groups,TCM syndrome scores before and after treatment,postmenstrual recovery rate,pregnancy outcome(pregnancy rate and pregnancy at 6 weeks and 12 weeks spontaneous abortion rate).Results The total effective rate of treatment in the observation group was 94.29%(33/35),which was higher than the control group of 77.43%(25/35)(P<0.05);The score of TCM syndromes in the observation group was lower than that in the control group after treatment(P<0.05);The recovery rate of menstrual flow in the observation group at 1 month,2 months and 3 months after operation was higher than that in the control group(P<0.05);Hysteroscopic uterine recovery in the observation group at 3 months after operation was better than that in the control group(P<0.05);spontaneous abortion rate in the observation group at 6 weeks and 12 weeks was lower than that in the control group(P<0.05).Conclusion The effects of traditional Chinese and Western Medicine on RSA caused by IUA is better than that of Western medicine alone.
作者
黄萍丽
黄钟燕
HUANG Ping-Li;HUANG Zhong-Yan(Guangxi Zhuang Autonomous Region Maternal and Child Health Hospital,Nanning 530003,China)
出处
《中国药物经济学》
2020年第2期62-64,68,共4页
China Journal of Pharmaceutical Economics
关键词
宫腔粘连
复发性流产
中西医结合
Intrauterine adhesions
Recurrent miscarriage
Integrated traditional Chinese and western medicine