摘要
中医将情志因素视为疾病发生的重要原因之一。现代研究发现,情志失调与卵巢功能过早衰退间存在紧密关联,负面情绪可通过干扰以下丘脑为主导的神经内分泌功能活动影响卵泡生长发育,表现为以高促性腺激素及低雌激素为主的内分泌异常。与此同时,异常的内分泌环境又可促进大脑负面情绪的产生,二者相互作用,恶性循环,使得卵巢功能进一步受损。情志活动是人体对外应答的产物,情志过极可致五脏气机升降出入运行失常,其中以心、肝、脾三脏为最甚:过喜伤心,悲忧亦耗散心气,无力化赤为血,血脉失充;怒致气机上炎,肝失调达而气血逆乱;思则气结不行,津停成水湿,蕴于中焦而致枢机不利,脾无力运化升清,四脏皆不得养,最终影响肾精肾水化生,天癸无源,冲任不盛,胞宫失濡,故而出现经行异常及生殖功能下降等类围绝经期症状。年未至而经水早断,多由于各脏功能失常。患者负面情绪和精神心理压力的增加既是疾病发展的诱因也是必然结果,患者不仅出现身体素质下降,同时其工作及两性生活也受到极大困扰,情志活动向更为糟糕的方向发展。故在治疗本病时医者应积极疏导患者的负面情绪及心态调适,着重调整各脏腑气机及其功能、恢复正常的神经内分泌环境,身心同治以促进卵巢功能的恢复。
TCM regards emotional factors as one of the important causes of disease.Modern research has found a strong link between emotional disorders and premature ovarian decline.Negative emotions can affect follicular growth and development by interfering with neuroendocrine activities dominated by the hypothalamus,which is manifested as endocrine abnormalities dominated by high gonadotropin and low estrogen.At the same time,abnormal endocrine conditions can promote negative emotions in the brain,the two interact,forming a vicious circle,making further damage to ovarian function.Emotional activity is a product of the body’s external response,too much emotion can lead to abnormal operation of the five viscera Qi(气),in which the heart,liver and spleen are the most:excessive joy damages heart,sorrow also dissipates heart,makes it unable to regulate blood,blood loses nutrition;Anger causes Qi to rush upward,and liver disorders lead to Qi and blood inversed chaos;Excessive thinking leads to Qi fail to run,moisture are generated from the inside,and the central focal pivot is not good.The spleen is weak,and the four zang organs are not nourishing,which ultimately affects the generation of kidney essence and kidney water.Tiankui(天癸)has no source,Chong(冲)channel and Ren(任)channel is not filled,uterus loses support,hence the occurrence of menstrual abnormalities and reproductive function decline and other perimenopausal symptoms appear.Menstruation breaks off earlier,because each viscera function is abnormal.The increase of patients’negative emotions and mental and psychological pressure is both the inducement and inevitable result of the development of the disease.The patients not only show a decline in physical quality,but also suffer great difficulties in their work and sexual life,and their emotional activities develope to a worse direction.Therefore,in the treatment of this disease,doctors should actively ease the patient’s negative emotions and give mentality adjustment,focusing on the adjustment of the viscera Qi and function,restore the normal neuroendocrine environment,promote the recovery of ovarian function by synchronic treatment of the body and mind.
出处
《中医临床研究》
2023年第3期133-138,共6页
Clinical Journal Of Chinese Medicine
基金
上海市普陀区科委卫生健康系统科技创新重点项目(ptkwws201906)
关键词
情志失调
卵巢功能
神经内分泌
脏腑气机
Emotional disorders
Ovarian function
Neuroendocrine
Viscera Qi activity
