摘要
血管性痴呆(vascular dementia,VD)是第二大常见的痴呆病因,具有一定的可治疗性和预防性,中医药治疗痴呆能通过多靶点、多途径、多方位调控VD相关的信号传导通路和基因靶点。VD为本虚标实之证,其中脾肾亏虚为根本病机,痰瘀博结为基本病机。治宜攻补兼施,采用补气健脾、益肾填髓、豁痰开窍、活血化瘀的治疗策略。基于数据探讨历代医家治疗痴呆相关病证常用中药,以期促进未来中医药在VD方面的研究进展。
Vascular dementia(VD)is the second most common cause of dementia which has a certain therapeutic and preventive nature.Traditional Chinese medicine(TCM)treats dementia through regulating VD-associated signaling pathways and gene target through multi-target multiple pathways and multiple aspects.VD is the syndrome of deficiency in origin and excess in superficiality.Deficiency of spleen and kidney is the fundamental pathogenesis,and the phlegm and blood stasis is the basic pathogenesis.The treatment should be attacked and compensated concurrently,adopting the treatment strategy of tonifying Qi and strengthening spleen,tonifying kidney and supplementing the marrow,expelling phlegm and opening the orifices,promoting blood circulation and removing blood stasis.This paper discussed the TCM in the treatment of dementia to promote the research progress on TCM in VD.
作者
曹冰倩
谭峰
CAO Bingqian;TAN Feng(Foshan Traditional Chinese Medicine Hospital Affiliated to Guangzhou University of Chinese Medicine,Foshan 528000,Guangdong,China)
出处
《中华中医药学刊》
CAS
北大核心
2022年第5期62-67,共6页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81072947,81473470,81774423)
国家中医药管理局谭峰全国名老中医药专家传承工作室建设项目(国中医药人教发[2016]42号)
广东省自然科学基金重点项目(2014A030311033)
关键词
脾肾痰瘀
中医药
血管性痴呆
理论
phlegm and blood stasis in spleen and kidney
TCM
vascular dementia
theory
