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59例早、中期妊娠结核病患者的临床特征及预后

Clinical characteristics and prognosis of 59TB patients in early and mid-term pregnancy
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摘要 目的对59例早、中期妊娠合并结核病患者治疗后临床效果进行回顾性分析,寻求妊娠合并结核病诊治经验。方法对我院收治的59例早、中期妊娠合并结核患者,从妊娠期间结核病的临床变化及妊娠期间与终止妊娠后治疗效果进行分析与总结,观察其相关性。结果妊娠合并单纯性结核性胸膜炎时,对胸膜炎病情影响不大,治疗效果良好,甚至不影响妊娠;而伴有空洞型肺结核、血行播散型肺结核的妊娠患者,妊娠阶段与结核病情变化及治疗效果有关,且胎盘部位结核DNA阳性率较高。结论妊娠早、中期就诊的单纯性结核性胸膜炎临床影响较小。合并空洞型肺结核及血行播散型肺结核时妊娠时期选择就诊后临床影响较大,早期妊娠确诊后及时给予规范抗结核治疗方案,效果优于妊娠中晚期。 Objective To retrospectively analyze the clinical effects on 59tuberculosis(TB)patients in early and mid-term pregnancy after the treatment,and to explore the experience of diagnosis and treatment of TB combined with pregnancy.Methods For 59TB patients in early and mid-term pregnancy,the clinical changes of TB during pregnancy,the effects of treatment in the pregnancy and after its termination were analyzed and summarized,and the correlation was observed.Results The pregnancy complicated with simple tuberculous pleurisy had little effect on pleurisy condition,which had good therapeutic effect without affecting the pregnancy.However,for pregnant patients with cavernous TB and hematogenous TB,there was a significant correlation among the pregnancy stage,the changes of TB condition and therapeutic effects,and the positive rate of DNA in placental TB was relatively high.Conclusion The clinical effect of treatment on simple TB pleurisy in early and mid-term pregnancy is relatively small,while that on cavernous TB and hematogenous TB in pregnancy was great.The standard anti-tuberculosis treatment plan should be timely given after the confirmed diagnosis in early pregnancy.And the therapeutic effect in early pregnancy is better than that in the middle or late pregnancy.
作者 魏晗 郑立恒 侯志华 王国卫 孙克娟 WEI Han;ZHENG Li-heng;HOU Zhi-hua;WANG Guo-wei;SUN Ke-juan(Department of Obstetrics and Gynecology,Hebei Provincial Chest Hospital,Shijiazhuang050000,China)
出处 《中国误诊学杂志》 CAS 2019年第9期395-397,共3页 Chinese Journal of Misdiagnostics
关键词 结核 妊娠初期 妊娠中期 临床特征 妊娠结局 tuberculosis pregnancy trimester first pregnancy trimester second clinical features pregnancy outcome
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  • 1宋向凤,孙翔,王辉.雌孕激素对T淋巴细胞生长的调节作用[J].细胞与分子免疫学杂志,2005,21(2):249-249. 被引量:25
  • 2张蕾蕾,金华.结核病直接督导短程化疗策略的伦理学视角[J].医学与哲学(B),2007,28(5):66-67. 被引量:4
  • 3李金莲.妊娠合并粟粒型肺结核17例.中华结核和呼吸杂志,1998,21(6):343-343.
  • 4Patrizia Luppi. How immune mechanisms are affected by pregnancy[J]. Vaccine, 2003, 21(24): 3352-3357.
  • 5Whitacre CC. Sex differences in autoimmune disease[J]. Nature Immunology, 2001, 2(9): 777-780.
  • 6Lederman MM. Cell-mediated immunity and pregnancy[J]. Chest, 1984, 86(Suppl 3): 6-9.
  • 7Wilson CA, Mrose SA, Thomas DW. Enhanced production of B lymphocytes after castration[J]. Blood, 1995, 185(6): 1535-1539.
  • 8Suenaga R, Evans MJ, Mitamura K, et al. Peripheral blood T cells and monocytes and B cell lines deried from patients with lupus express estrogen receptor transcripts similar to those of normal cells[J]. J Rheumatol, 1998, 25: 1305-1312.
  • 9Nhan-Chang C L,Jones T B. Tuberculosis in pregnancy[J].Clinical Obstetrics and Gynecology,2010,(02):311-321.
  • 10高微微.特殊人群结核病治疗[M]北京:科学出版社,2011.

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