摘要
目的研究老年人群中6种常见慢性病及其共患情况对全因死亡的影响,为制定健康老龄化慢病防控策略提供科学依据。方法利用中国老年健康影响因素追踪调查(CLHLS)数据,CLHLS在2011年对7080名65岁及以上人群进行基线调查,2014年随访一次,问卷内容包括调查对象人口统计学信息、生活方式与行为、慢性病相关信息。采用Stata 15.0进行t检验、χ~2检验。采用Cox比例风险模型分析6种常见慢性病及高发慢性病综合评分与老年人全因死亡的风险关联。结果2014年随访时有2121人死亡,死亡率为30.0%。多因素调整后,老年人患痴呆、癌症、糖尿病、肺部疾病、心血管疾病和高血压分别使全因死亡增加了113%(HR=2.13,95%CI:1.66~2.74),105%(HR=2.05,95%CI:1.39~3.03),59%(HR=1.59,95%CI:1.26~2.02),28%(HR=1.28,95%CI:1.12~1.45),13%(HR=1.13,95%CI:1.01~1.27),9%(HR=1.09,95%CI:1.01~1.19)。高发慢性病综合评分每增加1分,老年人群全因死亡风险增加46%(HR=1.46,95%CI:1.36~1.58)。高发慢性病综合评分为0.1~1.0、1.1~2.0、2.1~3.0、3.1~4.0和4.1~5.0分的老年人群慢性病死亡风险显著增加,危害比随着评分增加而呈增长趋势(HR值分别为1.17、1.72、2.41、4.63和11.65,P<0.01)。结论高血压、糖尿病、心血管疾病、肺部疾病、痴呆和癌症是老年人全因死亡的独立危险因素,而高发慢性病共患对死亡风险呈增长趋势。控制慢性病相关危险因素,预防慢性疾病的发生和发展,对提高老年人群期望寿命有着重要意义。
Objective To study the effects of six common chronic diseases and their multi-morbidity patterns on the all-cause death in the elderly,and to provide the scientific basis for prevention and control strategies for chronic diseases of healthy aging.Methods The data of Chinese Longitudinal Healthy Longevity Survey(CLHLS)were used in present study.7080 residents≥65 years old were included in the 2011 baseline survey and were followed up in 2014 by CLHLS.The investigation was performed with questionnaire which included the demographic information,lifestyle,behavior,chronic diseases information of subjects.The t test andχ~2 test were used to analyze the data,the used software was Stata 15.0.Cox proportional hazards model was used to analyze the correlation between six common chronic diseases,comprehensive scores of high incidence chronic diseases and all-cause death in the elderly.Results In following up of 2014,2121 subjects died,the mortality was 30.0%.After adjustment for confounding factors,the elderly with dementia,cancer,diabetes,lung disease,cardiovascular disease and hypertension increased all-cause mortality by 113%(HR=2.13,95%CI:1.66-2.74),105%(HR=2.05,95%CI:1.39-3.03),59%(HR=1.59,95%CI:1.26-2.02),28%(HR=1.28,95%CI:1.12-1.45),13%(HR=1.13,95%CI:1.01-1.27),9%(HR=1.09,95%CI:1.01-1.19),respectively.In the comprehensive scores of high incidence chronic diseases,each point could increase the all-cause death risk(46%)in the elderly(HR=1.46,95%CI:1.36-1.58).The risk of chronic diseases death significantly increased in the elderly with comprehensive scores of 0.1-1.0,1.1-2.0,2.1-3.0,3.1-4.0 and 4.1-5.0;and the hazard ratio increased with the score(HR values were 1.17,1.72,2.41,4.63 and 11.65 respectively,P<0.01).Conclusion Hypertension,diabetes,cardiovascular disease,lung disease,dementia and cancer are independent risk factors for all-cause death in the elderly,and multi-morbidity of high incidence chronic diseases has an increase in the death risk.Controlling the risk factors related to chronic diseases,and preventing the occurrence and development of chronic diseases has the great significance for improving the life expectancy of the elderly.
作者
曹志
程杨杨
王媛
孙俐
徐富升
王耀刚
CAO Zhi;CHENG Yang-yang;WANG Yuan;SUN Li;XU Fu-sheng;WANG Yao-gang(School of Public Health,Tianjin Medical University,Tianjin 300070,China;不详)
出处
《中国慢性病预防与控制》
CAS
CSCD
北大核心
2020年第1期20-23,共4页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
国家自然科学基金项目(91746205,71673199,71704131).
关键词
慢性病
全因死亡
疾病共患
老年人群
Chronic disease
All-cause death
Multi-morbidity
Elderly
