摘要
[目的]分析1987—2017年苏州市恶性肿瘤死亡流行特征及变化趋势。[方法]收集苏州市恶性肿瘤死亡数据,统计粗死亡率、中国人口标化死亡率(中标率)、世界人口标化死亡率(世标率)、累积率(0~74岁)及主要癌种构成比,采用年度变化百分比(annual percentage change,APC)估计恶性肿瘤死亡率的变化趋势。[结果]1987—2017年苏州市居民因恶性肿瘤死亡343037例,2017年粗死亡率升至213.62/10万,APC为1.04%,变化趋势差异有统计学意义(t=-24.85,P<0.001);中标率、世标率和累积率(0~74岁)分别下降至91.67/10万、90.44/10万、9.86%,APC分别为-1.38%、-1.43%和-1.87%,变化趋势差异有统计学意义(t值分别为19.45、20.56、20.25,P均<0.001)。男女性死亡率相关指标变化趋势一致,且男性标化死亡率约为女性的2倍。恶性肿瘤年龄别死亡率在30岁前处于较低水平,随着年龄的增加,年龄别死亡率呈现上升趋势,但30~69岁年龄组随着年份的增加死亡率下降。肺癌、胃癌、肝癌、结直肠癌、胰腺癌和食管癌一直是苏州市主要恶性肿瘤死亡原因。1987—2017年间,肺癌由主要恶性肿瘤死因的第3位跃至首位,结直肠癌由第5位升至第4位。[结论]虽然苏州市居民恶性肿瘤标化死亡率逐渐下降,但粗死亡率呈现上升趋势,不同时期主要恶性肿瘤顺位也发生了变化,应因地制宜采取有效的预防控制措施。
[Purpose]To analyze the epidemiological characteristics and trend of cancer mortality in Suzhou during 1987 to 2017.[Methods]The cancer death data in Suzhou from 1987 to 2017 was collected.The crude mortality rate,age-standardized mortality rate by Chinese standard population(ASMRC)and by Segi’s world standard population(ASMRW),cumulative rate(0~74 years old)and the proportion major cancers were calculated.Annual percentage changes(APC)were estimated to examine the trend of cancer mortality.[Results]A total of 343037 residents died of cancers in Suzhou from 1987 to 2017,with a crude mortality rate of 213.62/105,ASMRC of 91.67/105,ASMRW of 90.44/105 and cumulative rate(0~74 years old)of 9.86%in 2017.Crude mortality rate showed an increased trend(APC=1.04%,t=-24.85,P<0.001),however,the ASMRC,ASMRW and cumulative rate showed a decreased trend(APC=-1.38%,-1.43%and-1.87%,t=19.45,20.56 and20.25,respectively,all P<0.001).The change trend of cancer mortality was similar in different gender.The age-standardized mortality in male was about 2 times of that in female.The cancer mortality rate was at low level before 30 years,and increased rapidly afterwards;however,the cancer mortality rate of 36~69 age group declined with the increase of years.The cancers of lung,stomach,liver,colorectum,pancreas and esophagus composed the major cause of cancer mortality in Suzhou.The rank of lung cancer ascended from third to first and colorectal cancer ascended from fifth to fourth of cancer deaths,from 1987 to 2017.[Conclusion]Although the age-standardized cancer mortality demonstrated a declining trend,the crude rate was rising;the rank of major cancer death has changed in Suzhou from 1987 to 2017.
作者
黄春妍
王临池
陆艳
华钰洁
胡一河
黄桥梁
张钧
HUANG Chun-yan;WANG Lin-chi;LU Yan;HUA Yu-jie;HU Yi-he;HUANG Qiao-liang;ZHANG Jun(Suzhou Center for Disease Prevention and Control,Suzhou 215004,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2020年第2期90-95,共6页
China Cancer
基金
苏州市科技局民生科技(科技示范)项目(SS201807)
苏州市医学重点学科流行病学(慢性病防治)(Szxk201816)
苏州市重大疾病、传染病预防和控制关键技术(研究)项目(GWZX201601)
苏州市科教兴卫项目(KJXW2016046).
