摘要
目的对冠心病患者采用阿托伐他汀+曲美他嗪疗治后的临床效果及安全性进行观察和分析。方法纳入研究资料为100例本院于2017年6月-2020年6月期间收治的冠心病患者,将其按照信封法随机分为常规组和实验组,各50例;分别给予曲美他嗪口服治疗和阿托伐他汀+曲美他嗪治疗,对比分析两种治疗方案对冠心病患者的临床治疗效果。结果治疗总有效率实验组为96.00%较常规组的80.00%更高,心绞痛发作频率实验组为(2.28±0.11)次/周,较常规组的(3.98±0.55)次/周更低,心绞痛发作持续时间实验组为(2.22±0.11)min较常规组的(4.45±0.19)min用时更短,以上研究数据组间差异具有统计学意义(P<0.05)。两组患者治疗过程中均未出现明显的不良反应,组间差异无统计学意义(P>0.05),具有可对比性。结论阿托伐他汀+曲美他嗪可以改善冠心病患者的血脂及心绞痛情况,同时还兼具治疗安全性及有效性,更加适用于冠心病的临床治疗。
Objective To observe and analyze clinical effect and safety of atorvastatin+trimetazidine on patients with coronary heart disease.Methods The paper chose 100 patients with coronary heart disease treated in our hospital from June 2017 to June 2020 for study,and divided them into routine group and experimental group randomly according to envelope method,with 50 cases in each group,trimetazidine oral treatment and atorvastatin+trimetazidine treatment was applied respectively.Clinical curative effect of patients with coronary heart disease was compared and analyzed between two treatment schemes.Results Total effective rate of experimental group was 96.00%,higher than 80.00%of routine group.Frequency of angina pectoris attack in experimental group was(2.28±0.11)times/week,lower than(3.98±0.55)times/week of routine group.Duration of angina pectoris attack in experimental group was(2.22±0.11)min,shorter than(4.45±0.19)min of routine group,difference between above research data groups was statistically significant,(P<0.05).There were no obvious adverse reactions during treatment of two groups,difference between groups was not statistically significant,(P>0.05),data was comparable.Conclusion Atorvastatin+trimetazidine can improve blood lipid and angina pectoris of patients with coronary heart disease,with safety and effect,which is suitable for clinical treatment of coronary heart disease.
作者
张桂光
王立春
ZHANG Guiguang;WANG Lichun(Internal Medicine Department,Anqiu City Shidui Township Hospital,Weifang,Shandong,262103;Nursing Department,Anqiu City Shidui Town Health Center,Weifang,Shandong,262103)
出处
《智慧健康》
2022年第24期192-195,共4页
Smart Healthcare
关键词
阿托伐他汀
曲美他嗪
冠心病
治疗总有效率
安全性
Atorvastatin
Trimetazidine
Coronary heart disease
Total effective rate
Safety
