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生长抑素治疗肝炎肝硬化消化道出血的临床效果观察 被引量:2

Clinical Effect of Somatostatin in the Treatment of Gastrointestinal Bleeding in Patients with Hepatitis Cirrhosis
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摘要 目的探究分析生长抑素治疗肝炎肝硬化消化道出血的临床效果。方法将江苏连云港市灌云县人民医院于2019年12月至2020年12月收治的60例肝炎肝硬化消化道出血患者纳入本组研究,按照随机数字表法将其均分为两组,并对其展开不同治疗方式的分组探讨。两组患者均采用补血、纠正酸碱、水电解质平衡等常规治疗,对照组(30例)患者在常规治疗的基础上联合奥曲肽治疗,观察组(30例)患者在对照组的治疗基础上联合生长抑素治疗,对比两种不同治疗方式对应患者的临床疗效。结果①观察组经过治疗,其临床总体疗效优于对照组;②观察组治疗观察期间,其药物不良反应率低于对照组;③观察组在止血时间、输血量、住院时间等治疗指标方面均优于对照组,且观察组的24h再出血率为0%,明显低于对照组的6.67%。以上数据经SPSS 22.0统计学软件分析对比均显示P<0.05。结论生长抑素在治疗肝炎肝硬化消化道出血过程中可以优化治疗指标,起到快速止血的作用,有助于降低不良反应,提高治疗效率,促进患者早日康复。 Objective To explore and analyze the clinical effect of somatostatin in the treatment of gastrointestinal bleeding in patients with hepatitis cirrhosis.Methods Sixty cases of liver cirrhosis patients with gastrointestinal bleeding in Guanyun County People’s Hospital hospital from December 2019 to December 2020 were included in this study.They were divided into two groups according to the random number table method,and the different treatment methods were discussed.The control group(30 cases)was treated with octreotide on the basis of conventional treatment,and the observation group(30 cases)was treated with somatostatin on the basis of the control group.The clinical efficacy of two different treatment methods was compared.Results①After treatment,the overall clinical efficacy of the observation group was better than that of the control group.②During the observation period,the drug toxicity rate of the observation group was lower than that of the control group.③The observation group was superior to the control group in hemostasis time,blood transfusion volume,hospital stay and other treatment indicators,and the 24-hour rebleeding rate of the observation group was 0%,which was significantly lower than 6.67%of the control group.The above data were analyzed and compared by SPSS 22.0 statistical software(P<0.05).Conclusion Somatostatin in the treatment of liver cirrhosis in the process of gastrointestinal bleeding can optimize the treatment index,play a role in rapid hemostasis,help to reduce adverse reactions,improve treatment efficiency,promote the early recovery of patients.
作者 程海燕 CHENG Hai-yan(Guanyun County People’s Hospital,Lianyungang,Jiangsu 222200)
出处 《智慧健康》 2021年第20期136-138,共3页 Smart Healthcare
关键词 肝炎 肝硬化 消化道出血 生长抑素 临床效果 Hepatitis Cirrhosis Gastrointestinal bleeding Somatostatin Clinical effect
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