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血清甲状腺激素检测在诊断孕期甲状腺中的应用价值

Application Value of Serum Thyroid Hormone Detection in Diagnosis of Thyroid Gland during Pregnancy
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摘要 目的探讨血清甲状腺激素检测在诊断孕期甲状腺中的应用价值。方法选择自2019年1月至2020年6月来我院就诊的200例孕期甲状腺疾病患者作为本次的研究对象,根据其所患甲状腺疾病不同分为亚甲减组80例、甲减组60例以及甲亢组60例,另招募60例健康孕妇志愿者作为对照组。检测其血清甲状腺激素,对所有数据进行统计学分析,当P<0.05时,认为差异有统计学意义。结果亚甲减组TSH水平高于对照组,且P<0.05差异有统计学意义,亚甲减组FT3、FT4、TT3、TT4与对照组无统计学意义上差距,P>0.05;甲减组TSH水平高于对照组,甲减组FT3、FT4、TT3、TT4水平低于对照组,且P<0.05差异有统计学意义;甲亢组TSH水平低于对照组,甲亢组FT3、FT4、TT3、TT4水平高于对照组且P<0.05差异有统计学意义。结论血清甲状腺激素可以灵敏的反应孕期甲状腺状况,可以及时反应孕期甲状患病情况,有重要临床应用价值。 Objective To explore the value of serum thyroid hormone detection in the diagnosis of thyroid during pregnancy.Methods 200 patients with thyroid diseases during pregnancy who came to our hospital from January 2019 to June 2020 were selected as the subjects of this study.According to their different thyroid diseases,they were divided into 80 cases of subthyroidism group,60 cases of hypothyroidism group and 60 cases of hyperthyroidism group.Another 60 healthy pregnant volunteers were recruited as the control group.Serum thyroid hormone was detected and all data were statistically analyzed.When P<0.05,the difference was considered to be statistically significant.Results The TSH level of the subthyroidism group was higher than that of the control group,and the difference was statistically significant(P<0.05).FT3,FT4,TT3 and TT4 of the subthyroidism group were not significantly different from those of the control group(P>0.05).The TSH level of the hypothyroidism group was higher than that of the control group,while the FT3,FT4,TT3 and TT4 levels of the hypothyroidism group were lower than those of the control group,and the difference of P<0.05 was statistically significant.The TSH level of the hyperthyroidism group was lower than that of the control group,while the FT3,FT4,TT3 and TT4 levels of the hyperthyroidism group were higher than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Serum thyroid hormone can be sensitive to the status of the thyroid during pregnancy,can be timely response to thyroid disease during pregnancy,has important clinical application value.
作者 黄楚妮 肖俊锐 张成发 HUANG Chu-ni;XIAO Jun-rui;ZHANG Cheng-fa(Shantou Hospital of Traditional Chinese Medicine,Clinical Laboratory,Shantou,Guangdong 515031)
出处 《智慧健康》 2021年第10期6-8,共3页 Smart Healthcare
关键词 血清甲状腺激素 孕期 甲状腺激素 诊断 筛查 应用价值 Serum thyroid hormone Pregnancy Thyroid hormone Diagnosis Screening Application value
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