摘要
目的探讨先兆流产患者服用保胎无忧散后行低剂量黄体酮治疗的影响。方法选取2018年02月至2019年12月妇科收治的先兆流产患者210例,随机分为两组(观察组105例、对照组105例)。两组均给予常规治疗,对照组在此基础上给予黄体酮注射治疗。观察组常规治疗的基础上给予低剂量黄体酮联合保胎无忧散治疗。比较两组患者治疗效果、临床症状缓解时间、不良反应发生情况、血清绒毛膜促性腺激素(human choionic gonadotophin,HCG)、孕酮、糖类抗原125(carbohydrate antigen,CA125)水平变化。结果治疗后观察组血清HCG、孕酮水平高于对照组,观察组CA125水平低于对照组(P<0.05)。观察组治疗总有效率优于对照组,组间差异有统计学意义(P<0.05)。观察组患者阴道流血、腰痛、腹痛缓解时间均优于对照组,组间差异有统计学意义(P<0.05)。两组患者不良反应发生率无显著差异(P>0.05)。结论先兆流产患者行低剂量黄体酮联合保胎无忧散治疗,能够加快患者临床症状的缓解,改善临床治疗有效率,药物作用安全,具有重要的临床意义。
Objective To investigate the effect of low-dose progesterone on patients with threatened abortion after taking Baotai Wuyou Powder.Methods 210 patients with threatened abortion from February 2018 to December 2019 were randomly divided into control group(n=105)and observation group(n=105).Both groups were given routine treatment,and the control group was given progesterone injection on this basis.On the basis of routine treatment,the observation group was treated with low-dose progesterone combined with Baofei no-worry powder.The therapeutic effect,the time of clinical symptom relief,the occurrence of adverse reactions and the levels of serum chorionic gonadotropin(HCG),progesterone and carbohydrate antigen 125(CA125)were compared between the two groups.Results After treatment,the levels of serum HCG and progesterone in the observation group were higher than those in the control group,while the level of CA125 in the observation(P<0.05).The total effective rate of the observation group was better than that of the control group,and the difference between groups was statistically significant(P<0.05).The relief time of vaginal bleeding,low back pain and abdominal pain in the observation group was better than that in the control group,and the difference between the two groups was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The treatment of patients with threatened abortion with low-dose progesterone combined with Baofeiwusan can accelerate the relief of clinical symptoms,improve the effective rate of clinical treatment,and the drug effect is safe,which has important clinical significance.
作者
周丽
张莉
ZHOU Li;ZHANG Li(Nantong Hospital of traditional Chinese Medicine,Gynecology Department,Nantong,Jiangsu 226001)
出处
《智慧健康》
2021年第10期122-124,共3页
Smart Healthcare
关键词
先兆流产
黄体酮
保胎无忧散
临床效果
安全性
Threatened abortion
Progesterone
Baofei worry-free powder
Clinical effect
Safety
