摘要
目的分析全科医学治疗在溃疡性结肠炎患者中的临床作用。方法截取自2018年12月至2019年12月本科治疗的溃疡性结肠炎患者160例,采用随机数字法分为观察组(常规治疗联合全科医学治疗)和对照组(常规治疗),分别对比两组患者治疗后的临床症状改善情况、生活质量、血清IL-17、IL-23、临床疗效以及不良反应。结果(1)对比两组患者临床疗效:观察组患者临床疗效与对照组患者临床疗效相比差距较大,两组对比有统计学意义(P<0.05)。(2)对比两组患者症状改善情况:实验数据表明,观察组患者充血水肿、黏膜糜烂、粘膜溃疡症状改善情况明显高于对照组患者,两组患者数据对比有统计学意义(P<0.05)。(3)对比两组患者不良反应发生率:实验数据表明,观察组患者腹泻、腹痛、血便出现的几率与对照组患者相比差距显著,两组对比有统计学意义(P<0.05)。(4)对比两组患者生活质量:实验数据表明,观察组患者精神健康、社会功能、生理功能与对照组患者相比差距显著,两组对比有统计学意义(P<0.05)。(5)对比两组患者血清IL-17、IL-23:实验数据表明,观察组患者血清IL-17、IL-23与对照组患者相比差距显著,两组对比有统计学意义(P<0.05)。结论对溃疡性结肠炎患者采用全科医学治疗模式进行治疗效果显著,相较于常规治疗的方式更具有较高的临床作用价值。
Objective To analyze the clinical effect of general medical treatment in patients with ulcerative colitis.Methods One hundred and sixty patients with ulcerative colitis who received undergraduate treatment from December 2018 to December 2019 were randomly divided into observation group(conventional treatment combined with general medical treatment)and control group(conventional treatment).The improvement of clinical symptoms,quality of life,serum IL-17,IL-23,clinical efficacy and adverse reactions of the two groups were compared respectively.Results(1)Comparison of the clinical efficacy of the two groups:the difference between the clinical efficacy of the observation group and that of the control group was statistically significant(P<0.05).(2)The improvement of symptoms in the two groups was compared:the experimental data showed that the symptoms of congestion,edema,mucosal erosion and mucosal ulcer in the observation group were significantly higher than those in the control group,with statistical significance(P<0.05).(3)Compared the incidence of adverse reactions between the two groups:experimental data showed that the incidence of diarrhea,abdominal pain and bloody stool in the observation group was significantly lower than that in the control group,with statistical significance(P<0.05).(4)The quality of life of the two groups was compared:the experimental data showed that the mental health,social function and physiological function of the observation group were significantly different from those of the control group,and the comparison between the two groups was statistically significant(P<0.05).(5)Comparison of two groups of patients with serum IL-17,IL-23:experimental data show that the observation group of patients with serum IL-17,IL-23 compared with the control group,the difference was statistically significant(P<0.05).Conclusion Compared with the conventional treatment,for ulcerative colitis patients with general medical treatment mode for treatment effect is significant,it has higher clinical value.
作者
优拉太
Youlatai(Xinghai County Tibetan Hospital,Hainan,Qinghai 813399)
出处
《智慧健康》
2020年第25期58-60,共3页
Smart Healthcare
关键词
全科医学
溃疡性结肠炎
临床作用
General medicine
Ulcerative colitis
Clinical effect
