摘要
目的了解江西省HIV/AIDS患者(PLWHA)吸烟行为与神经认知功能的关系。方法采用方便抽样方法,在江西省抗逆转录病毒治疗(ART)定点医院进行CD4^+T细胞计数检测的PLWHA中抽取85例进行神经心理测验,分析PLWHA吸烟行为与神经认知功能的关系。结果PLWHA霍普金斯词语学习测验修订版(HVLT-R)(40.22±8.61)、简短视觉空间记忆测验修订版(BVMT-R)(46.18±12.06)、连线测验A(TMT A)(40.95±12.19)、符号编码分测验(BACSS)(28.04±16.57)、范畴流畅测验-动物命名(CF)(30.96±11.31)等5个分测验得分均低于全国常模(P<0.05)。多元线性回归分析显示词语学习(r=-0.368,β=-3.012,P=0.042)、视觉学习(r=-0.389,β=-3.653,P=0.001)、信息处理速度(r=-0.524,β=-5.205,P=0.002)等3个认知领域均与吸烟负相关,信息处理速度还受年龄影响。结论PLWHA普遍存在神经认知功能受损,吸烟严重影响PLWHA神经认知功能。
Objective To analyze the relationship between neurocognition function and smoking behavior among people living with HIV/AIDS(PLWHA)in Jiangxi province.Methods 85 cases of PLWHA who received the CD4^+T cell count detection in Jiangxi province ART hospital were selected by convenient sampling method,and then were examined by using HIV-related neuropsychological test battery,the association of neurocognition function and smoking behavior among PLWHA were analyzed.Results In PLWHA,5 scores of HVLT-R(40.22±8.61),BVMT-R(46.18±12.06),TMT A(40.95±12.19),BACSS(28.04±16.57),CF(30.96±11.31)were lower than Chinese norm(P<0.05).Multivariate linear regression analysis revealed that verbal learning(r=-0.368,β=-3.012,P=0.032),visual learning(r=-0.389,β=-3.653,P=0.001)and information processing speed(r=-0.524,β=-5.205,P=0.002)were negative correlation with smoking behavior,and information processing speed were also influenced by age.Conclusion PLWHA normally had multiple dimensions of neurocognitive impairment.Smoking behavior seriously damages PLWHA’s neurocognitive function.
作者
刘云
杨紫君
袁也丰
徐茜
曾欢
LIU Yun;YANG Zi-jun;YUAN Ye-feng;XU Xi;ZENG Huan(Nanchang Center for Disease Control and Prevention,The Collaboration Unit for Field Epidemiology of State Key Laboratory for Infectious Disease Prevention and Control,Jiangxi Provincal key Laboratory of Animal-origin and Vector-borne Diseases,Nanchang 330038,China)
出处
《中国健康教育》
北大核心
2019年第11期993-996,共4页
Chinese Journal of Health Education
基金
江西省卫生和计划生育委员会科技项目(20176036).
