摘要
目的了解山东省济南市孕妇碘营养状况,为及时采取有效的防治措施和科学指导孕妇补碘提供依据。方法2018—2021年,在山东省济南市12个区县开展孕妇碘营养状况调查,每个区县按东、西、南、中方位划分5个片区,每个片区抽取1个乡镇的20名孕妇,共4992人,并采集孕妇的盐样和尿样,检测样品的盐碘与尿碘含量。盐碘检测采用GB/T 13025.7《制盐工业通用试验方法碘的测定》,川盐及其他强化食用盐采用仲裁法;尿碘检测采用WS/T 107《尿中碘的砷铈催化分光光度测定方法》。按照不同年份,区县,孕期[孕早期(≤12周)、孕中期(13~27周)、孕晚期(≥28周)]对盐碘及尿碘进行分析。结果共监测孕妇食用盐盐样4992份,盐碘含量M(P^(25),P^(75))为22.31(18.18,25.59)mg/kg,碘盐覆盖率为88.92%(4439份),合格碘盐食用率为72.96%(3642份),不同年份、不同区县的碘盐覆盖率(χ^(2)=72.54、271.04,P均<0.05)和合格碘盐食用率差异均有统计学意义(χ^(2)=43.03、492.25,P均<0.05),不同孕周的碘盐覆盖率(χ^(2)=1.07,P>0.05)和合格碘盐食用率差异均无统计学意义(χ^(2)=0.97,P>0.05)。监测孕妇尿碘4992份,尿碘M(P^(25),P^(75))为145.70(87.70,216.00)μg/L,不同年份、不同区县、不同孕周的尿碘水平差异均有统计学意义(H=21.97,348.78、41.18,P均<0.05),不同盐碘水平下的孕妇尿碘差异有统计学意义(H=13.23,P<0.05)。结论济南市孕妇碘营养水平总体处于轻度碘缺乏水平。济南市要继续推行食盐加碘消除碘缺乏病防治策略,加强孕妇的健康教育和碘营养的监测工作,坚持分类指导、科学补碘。
Objective To examine iodine nutrition status among pregnant women in Ji'nan city,Shandong province for providing evidence to effective improvement of iodine nutrition in pregnant women.Methods A monitoring survey was conducted among 4992 pregnant women recruited in 12 districts/counties of Ji′nan municipality,Shandong province during 2018–2021;each of the districts/counties was divided into 5 geographical regions and 20 pregnant women were selected from one subdistrict/town in each of the 5 regions.Table salt samples were collected from households of the pregnant women and urine samples of the pregnant women were also collected.Iodine content of table salt samples was measured with direct titration listed in the General Test Method for Salt Industry:Determination of Iodine(GB/T13025.7)and that of well salt and other fortified table salt samples was determined with arbitration method.Urinary iodine was detected using arsenic cerium catalytic spectrophotometry stated in WS/T107 issued by National Health and Family Planning Commission.Year-and trimester-specific urinary iodine were analyzed.Results The median(25%percentile[P^(25)],75%percentile[P^(75)])of iodine content was 22.31(18.18,25.59)mg/kg for all the 4992 table salt samples.The coverage rate of iodized table salt was 88.92%(4439 samples)and the usage rate of qualified iodized table salt was 72.96%(3642 samples).There were significant yearly and regional differences in iodized salt coverage(χ^(2)=72.54,χ^(2)=271.04;both P<0.05)and qualified iodized table salt usage rate(χ^(2)=43.03,χ^(2)=492.25,both P<0.05);but the iodized salt coverage and qualified iodized table salt usage rate were not significantly different among the pregnant women in various trimesters of pregnancy(χ^(2)=1.07,χ^(2)=0.97;both P>0.05).The median(P^(25),P^(75))of urinary iodine was 145.70(87.70,216.00)μg/L for the 4992 pregnant women.The urinary iodine concentration differed significantly among the pregnant women surveyed in different years(H=21.97),from various districts/towns(H=348.78),during various trimesters of pregnancy(H=41.18),and consuming table salt with different iodine content(H=13.23)(P<0.05 for all).Conclusion Mild iodine deficiency existed among pregnant women in Ji'nan city during 2018−2021,suggesting that relevant measures should be taken to prevent iodine deficiency in the pregnant women.
作者
王勤富
曹萌
王志飞
时振东
WANG Qinfu;CAO Meng;WANG Zhifei;SHI Zhendong(Endemic Disease Control Institute,Ji'nan Municipal Center for Disease Control and Prevention,Jinan 250021,China;Jining Medical University,Jining 272113,China)
出处
《中国公共卫生》
CAS
CSCD
北大核心
2023年第11期1480-1484,共5页
Chinese Journal of Public Health
基金
济南市卫生健康委员会科技计划项目(2021–公–08)
关键词
孕妇
碘营养
盐类
尿
济南
pregnant women
iodine nutrition
salt
urine
Ji′nan city
