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锦州市≥40岁体检人群卒中患病风险及影响因素

Analysis of risk and factors influencing stroke among a population≥40 years of age in Jinzhou
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摘要 目的分析卒中高危人群患病风险的影响因素,为制定防治措施提供依据。方法选取2021年1月-2022年1月在锦州医科大学第一附属医院完成健康体检并同时进行脑血管血流动力学积分值(cerebrovascular hemodynamic accumulative score,CVHAS)评估的体检人群,对符合要求的对象进行问卷调查。收集体检者的资料,包括年龄、性别、体质量指数(body mass index,BMI)、舒张压(diastolic blood pressure,DBP)、收缩压(systolic blood pressure,SBP)、空腹血糖(fasting plasma glucose,FPG)、总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、尿酸(uric acid,UA)、同型半胱氨酸(homocysteine,Hcy)和健康问卷信息(包括吸烟情况、饮酒情况、运动情况及家族史)。应用单因素logistic回归分析卒中高危人群患病风险的影响因素。结果锦州市≥40岁体检人群中共有效调查10185名,其中卒中高危人群2855名,占总调查对象的28.02%。单因素分析结果显示,高危人群年龄、性别、吸烟史、饮酒史、BMI、SBP、DBP、TC、TG、HDL-C、FPG、Hcy水平与低危人群比较,差异有统计学意义(P<0.05);LDL-C、UA水平和家族史比较,差异无统计学意义(P>0.05)。二元logistic回归分析显示,男性、吸烟、饮酒、年龄增大、高BMI、高DBP、高TG和FPG升高是卒中患病风险的独立危险因素,差异有统计学意义(P<0.05)。结论锦州市≥40岁体检人群卒中高危人群检出率较高,应加强筛查工作,并通过健康管理和对目标人群的健康教育等措施,降低卒中发生率。 Objective To analyze the factors influencing the risk of stroke in a high-risk population to provide a basis for formulating prevention and treatment measures.Methods From January 2021 to January2022,people who underwent physical examinations and were simultaneously examined for cerebrovascular hemodynamic accumulative score(CVHAS)at the First Affiliated Hospital of Jinzhou Medical University were selected and asked to complete a questionnaire survey.The following data were collected:age;gender;body mass index;diastolic blood pressure and systolic blood pressure;fasting plasma glucose,total cholesterol,triglycerides,high density lipoprotein cholesterol,low density lipoprotein cholesterol,uric acid,and homocysteine levels;and a health questionnaire,including smoking,alcohol consumption,exercise,and family history.Univariate and logistic regression analyses were used to analyze the factors influencing stroke in a high-risk population.Results A total of 10185 subjects≥40 years of age were investigated in Jinzhou City,among whom 2855 were at high risk of stroke(28.02%of all subjects).Univariate analysis showed that age,gender,smoking history,alcohol consumption history,body mass index,systolic blood pressure,diastolic blood pressure,and total cholesterol,triglycerides,high density lipoprotein cholesterol,fasting plasma glucose,and homocysteine levels in the high-risk group were compared with those in low-risk group,the difference was statistically significant(P<0.05).There was no significant difference in the family history of stroke,and low density lipoprotein cholesterol and uric acid levels between the two groups(P>0.05).Binary logistic regression analysis showed that male gender,smoking,alcohol consumption,increased age,increased body mass index,increased diastolic blood pressure,increased triglycerides level,and increased fasting plasma glucose level were independent risk factors for stroke risk(P<0.05).Conclusions The prevalence of a high-risk population for stroke based on physical examination in a population≥40 years of age in Jinzhou City is high.It is necessary to strengthen screening of the population,and a reduction in the incidence of stroke through health management and health education for the high-risk population.
作者 屈一平 徐锦江 QYU Yi-ping;XU Jin-jiang(Jinzhou Medical University,Jinzhou,Liaoning 121000,China;不详)
出处 《慢性病学杂志》 2022年第11期1606-1610,共5页 Chronic Pathematology Journal
关键词 卒中 高血压 血脂 高危人群 脑血管血流动力学 Stroke High blood pressure Blood lipid High-risk group Cerebrovascular hemodynamics
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