妊娠早期甲状腺功能异常对妊娠期糖尿病发病情况及妊娠结局的影响被引量：2

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摘要目的探讨妊娠早期甲状腺功能异常对妊娠期糖尿病发病情况及妊娠结局的影响。方法选取2018年12月至2020年6月就诊于香港大学深圳医院妇产科的孕妇207例作为研究对象,其中确诊为妊娠早期甲状腺功能减退的孕妇95例,确诊为妊娠早期甲状腺自身抗体阳性的45例,甲状腺功能正常的孕妇67例,系统收集患者的一般资料(年龄、体质量、孕周、经产次数等)、临床资料(甲状腺功能检测、血糖检测、妊娠期晚期合并症、新生儿结局、孕妇产后24 h出血量等),采用回顾性病例对照研究方法进行综合整理分析数据,比较两组血糖水平、糖尿病发病情况及妊娠结局。结果甲状腺功能减退组空腹血糖(6.0±1.23)mmol/L及甲状腺过氧化物酶抗体(thyroid peroxidase antibody,TPOAb)阳性组空腹血糖(6.2±0.76)mmol/L较甲状腺功能正常组的(4.9±0.33)mmol/L上升明显,且不良妊娠结局发生率也明显增高,差异有统计学意义(P<0.05)。结论妊娠早期积极检测甲状腺功能、积极治疗甲状腺疾病对于降低妊娠期糖尿病及妊娠不良结局的发病率具有重要意义。

作者曹瑾

机构地区香港大学深圳医院妇产科

出处《慢性病学杂志》 2022年第7期1071-1073,1076,共4页 Chronic Pathematology Journal

关键词妊娠早期甲状腺功能异常妊娠期糖尿病妊娠结局

分类号 R714.256 [医药卫生—妇产科学]

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1沈振芳,钱靖,焦雪花,王安芳.甲巯咪唑片治疗甲状腺功能亢进患者的临床研究[J].中国临床药理学杂志,2020,36(18):2769-2771. 被引量：23
2妊娠合并糖尿病诊治指南（2014）[J].中华围产医学杂志,2014(8):537-545. 被引量：301
3无.妊娠和产后甲状腺疾病诊治指南[J].中华内分泌代谢杂志,2012,28(5):354-371. 被引量：640

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