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保乳术与改良根治术对乳腺癌患者血清肿瘤标志物水平及复发的影响 被引量:4

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摘要 目的探讨保乳术与改良根治术治疗乳腺癌患者的临床效果。方法回顾性分析2017年3月至2020年1月山东省聊城市第三人民医院接受手术治疗且于该时间段内完成2年术后随访的110例乳腺癌患者的临床资料。根据手术方法的不同进行分组,分为观察组(保乳术,n=52)与对照组(改良根治术,n=58),比较两组术后3 d血清肿瘤标志物水平变化情况以及并发症发生率和复发率情况。结果两组术前、术后血清糖类抗原153(CA153)、癌胚抗原(CEA)水平比较,差异无统计学意义(P>0.05);但两组术后血清CA153、CEA水平均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症总发生率为9.62%,低于对照组的24.14%,差异无统计学意义(P<0.05);术后随访2年,对照组复发率为1.72%,观察组复发率为5.77%,差异有统计学意义(P>0.05)。结论对乳腺癌患者而言,保乳术较改良根治术疗效更佳,可有效降低血清肿瘤标志物水平,减少术后并发症的发生,且无复发,值得借鉴。
出处 《慢性病学杂志》 2020年第10期1602-1603,共2页 Chronic Pathematology Journal
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