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甲状腺功能减退对妊娠期糖尿病患者血糖控制及胰岛素功能的影响 被引量:1

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摘要 目的观察妊娠期糖尿病(GDM)患者发生甲状腺功能减退(以下简称甲减)对血糖与胰岛素功能的影响。方法回顾性分析2017年1月至2018年9月深圳市龙岗区第三人民医院收治的62例GDM患者临床资料。依据甲状腺功能状况分为观察组(甲减,n=15)与对照组(正常,n=47)。比较两组血糖控制情况[餐后2h血糖(2hPG)、空腹血糖(FPG)及糖化血红蛋白(HbA1c)]、胰岛素功能[餐后2 h胰岛素(2hPINS)、空腹胰岛素(FINS)、胰岛素敏感性指数(ISI)及胰岛素抵抗指数(HOMA-IR)]。结果两组2hPG、FPG、HbA1c以及2hPINS水平比较,差异无统计学意义(P>0.05);观察组FINS、HOMA-IR高于对照组,ISI低于对照组,差异有统计学意义(P<0.05)。结论与甲状腺功能正常的GDM患者比较,GDM合并甲减患者的胰岛素抵抗程度更高,胰岛素敏感性更低,血糖指标水平相近。
作者 朱雅欣
出处 《慢性病学杂志》 2020年第3期390-391,394,共3页 Chronic Pathematology Journal
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