摘要
目的:探讨甘草泻心汤治疗艾滋病难治性口腔溃疡疗效及对患者口腔菌群的影响。方法:选取96例艾滋病难治性口腔溃疡患者作为研究对象,按照随机数字表法分为治疗组和对照组,每组各48例。对照组给予泼尼松+维生素B2治疗,治疗组在对照组治疗基础上联合使用甘草泻心汤治疗。比较两组治疗效果,并观察其对口腔链球菌、韦荣氏菌及奈瑟氏菌的影响。结果:治疗组临床治疗有效率显著优于对照组(P<0.05);治疗组治疗后中医证候积分减少率显著优于对照组(P<0.05);治疗组链球菌、韦荣氏菌改善情况显著优于对照组(P<0.05)。结论:甘草泻心汤治疗艾滋病难治性口腔溃疡疗效明显,可能与其能够调节口腔菌群、改善微生态有关。
Objective:To investigate the effect of licorice xiexin decoction on the treatment of refractory oral ulcer and its oral flora.Methods:96 patients with refractory oral ulcer were divided into treatment group and control group according to the random number table,48 cases in each group.The control group was treated with prednisone+vitamin B2,and the treatment group was treated withlicorice xiexin decoction on the basis of the control group.The effects of the two groups were compared and the effects of the two groups on Streptococcus oral,Bacillus veryceps and Neisseria were observed.Results:The effective rate of clinical treatment in the treatment group was significantly better than that in the control group(P<0.05).The reduction rate of TCM syndromes in post-treatment group was significantly better than that in control group(P<0.05).In the treatment group,Streptococcus and Veronella were significantly better than the control group(P<0.05).Conclusion:licorice xiexin decoction is effective in the treatment of intractable oral ulcer,which may be related to its ability to regulate oral flora and improve microecology.
作者
杨晓霞
李超锋
王炳恒
王双利
Yang Xiaoxia;Li Chaofeng;Wang Bingheng;Wang Shuangli(The 6th People's Hospital of Zhengzhou,Zhengzhou 450015,China)
出处
《亚太传统医药》
2020年第10期160-162,共3页
Asia-Pacific Traditional Medicine
基金
国家十二五科技重大专项(2012ZX10004301-005)
