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新疆某三甲医院妊娠期甲状腺激素水平参考范围的验证及差异性分析

Investigation and difference analysis of the reference range of thyroid hormone levels during pregnancy in a tertiary hospital in Xinjiang
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摘要 目的建立本单位检测系统妊娠期甲状腺激素水平参考范围,比较不同年龄阶段孕早、中、晚期女性甲状腺激素水平,为妊娠期健康监护提供理论依据。方法回顾性分析2019年6月-2021年6月本院正常妊娠期女性的甲状腺激素水平,比较不同孕期、不同年龄阶段女性甲状腺激素水平。结果孕早、中、晚期的FT3参考范围为4.45(3.38-5.67)pmol/L、4.08(3.26-5.308)pmol/L、3.94(3.242-5.012)pmol/L;孕早、中、晚期的FT4参考范围为15.46(12.494-20.815)pmol/L、13.66(12.071-18.842)pmol/L、13.27(12.062-16.541)pmol/L;孕早、中、晚期的TSH参考范围为2.14(0.485-3.971)mIU/L、2.11(0.523-3.941)mIU/L和2.12(0.611-3.961)mIU/L;全阶段孕期TPOAb参考范围为2.46(5.562-30.182)IU/Ml。结论不同孕期女性的FT3、FT4、TSH水平具有显著性差异(P<0.05),TPO水平无显著性差异(P>0.05),不同孕期女性的FT4水平分别在四组年龄分组中(≤25岁、>25岁-30岁、>30岁-35岁、>35岁)均具有显著性差异(P<0.05)。 Objective To establish the reference range of thyroid hormone levels during pregnancy in our unit’s detection system,compare the thyroid hormone levels of women of different ages in the first,middle and late stages of pregnancy,and provide a theoretical basis for health monitoring during pregnancy.Methods The thyroid levels of normal pregnant women in our hospital were retrospectively analyzed from June 2019 to June 2021,and the thyroid levels of women of different pregnancy periods and ages were analyzed and compared.Results The reference range of FT3 in the first,middle and late pregnancy was 4.45(3.38-5.67)pmol/L,4.08(3.26-5.308)pmol/L,3.94(3.242-5.012)pmol/L;FT4 was 46(12.494-20.815)pmol/L,13.66(12.071-18.842)pmol/L,13.27(12.062-16.541)pmol/L;TSH was 2.14(0.485-3.971)mIU/L,2.11(0.523-3.941)mIU/L,2.12(0.611-3.961)mIU/L;TPOAb reference range for all stages of pregnancy was 2.46(5.562-30.182)IU/Ml.Conclusions There are significant differences in FT3,FT4,and TSH levels of women in different pregnancy periods(P<0.05),but there is no significant difference in TPO level(P>0.05),There are significant differences in FT4 of four ages groups(>25-30 years old,>30-35 years old,>35 years old)(P<0.05).
作者 单蕾 李晟彬 刘伊宁 吴雄 刘洁 SHAN Lei;LI Shengbin;LIU Yining;WU Xiong;LIU Jie(Inspection Center,the Third People’s Hospital of Xinjiang Uygur Autonomous Region,Urumqi,830000,China)
出处 《新疆医学》 2024年第3期287-290,共4页 Xinjiang Medical Journal
基金 新疆维吾尔自治区第三人民医院院内课题(项目编号:2017ZB10)
关键词 妊娠期女性 甲状腺水平 参考范围 Pregnant woman Thyroid level Reference range
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