摘要
目的分析某院2016年-2020年甲状腺癌(TC)患者临床特征及中央区淋巴转移的危险因素。方法回顾性收集某院2016年-2020年收治的167例TC患者临床资料,记录患者临床病理特征、中央区淋巴结转移情况,设计基线资料填写表,询问并记录患者相关基线资料,将可能的影响因素纳入,经Logistic回归分析找出TC患者中央区淋巴结转移的危险因素。结果167例TC患者病理类型主要以乳头状癌为主,占86.83%;肿瘤直径>2cm、肿瘤分期Ⅲ-Ⅳ期占比略高,分别为52.10%、52.69%;中央区淋巴结转移率为26.95;中央区淋巴结转移TC患者肿瘤直径、包膜侵犯、微钙化、血流分级与未转移患者比较,差异有统计学意义(P<0.05);中央区淋巴结转移、未转移TC患者其他基线资料比较差异无统计学意义(P>0.05);经Logistics回归分析检验,结果显示,肿瘤直径>2 cm、包膜侵犯、微钙化、血流分级Ⅱ-Ⅲ级是TC患者中央区淋巴结转移的危险因素(OR>1,P<0.05)。结论新疆南疆某三甲医院2016年-2020年TC患者病理类型主要以乳头状癌为主,肿瘤直径>2cm、肿瘤分期Ⅲ-Ⅳ期占比略高,中央区淋巴结转移主要受肿瘤直径>2cm、包膜侵犯、微钙化、血流分级Ⅱ-Ⅲ级因素影响。
Objective To analyze the clinical characteristics of patients with thyroid cancer(TC)and the risk factors of lymphatic metastasis in central region in a Hospital from 2016 to 2020.Methods The clinical data of 167 TC patients admitted to a hospital from 2016 to 2020 were retrospectively collected.The clinicopathological characteristics and lymph node metastasis in central region of the patients were recorded.A baseline data filling form was designed,and relevant baseline data were questioned and recorded.Logistic regression analysis found the risk factors of central lymph node metastasis in TC patients.Results The pathological types of 167 TC patients were mainly papillary carcinoma,accounting for 86.83%.The proportion of tumor diameter>2 cm and tumor stageⅢ-Ⅳwas 52.10%and 52.69%,respectively.The rate of lymph node metastasis in central region was 26.95.There were statistically significant differences in tumor diameter,capsule invasion,microcalcification and blood flow grade between TC patients with lymph node metastasis in central region and those without metastasis(P<0.05).There was no significant difference in other baseline data between patients with lymph node metastasis and patients without metastasis in central region(P>0.05).Logistic regression analysis showed that tumor diameter>2 cm,capsule invasion,microcalcification and blood flow gradeⅡ-Ⅲwere risk factors for lymph node metastasis in central region of TC patients(OR>1,P<0.05).Conclusion Papillary carcinoma was the main pathologic type of TC patients in a third-class hospital in southern Xinjiang from 2016 to 2020,with tumor diameter>2 cm and tumor stageⅢ-Ⅳaccounting for a slightly higher proportion.Lymph node metastasis in central region was mainly affected by tumor diameter>2 cm,capsule invasion,microcalcification and blood flow gradeⅡ-Ⅲ.
作者
梅彩霞
MEI Caixia(Department of Endocrinology,Korla Hospital of The Second Division of Xinjiang Production and Construction Corps,Korla,841000,Xinjiang,China)
出处
《新疆医学》
2023年第2期159-162,共4页
Xinjiang Medical Journal
关键词
甲状腺癌
临床病理特征
淋巴结转移
包膜侵犯
微钙化
血流分级
Thyroid carcinoma
Clinicopathological features
Lymph node metastasis
Capsular invasion
Microcalcification
Blood flow classification
