摘要
目的探讨实验室指标对腹型过敏性紫癜发生胃肠道出血的预测价值,以提高早期诊断与治疗水平。方法回顾性分析2013年1月至2019年1月住院治疗的111例以腹痛为首发症状的过敏性紫癜患者的临床资料,对符合入组条件的患者按照有无胃肠道出血症状分为胃肠道出血组和无胃肠道出血组。分别检测儿童及成年患者白细胞、红细胞、血小板、中性粒细胞、淋巴细胞、嗜酸性粒细胞、平均血小板体积,并计算出中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值,分析以上实验室指标与胃肠道出血之间的相关性。结果111例腹型过敏性紫癜初诊患者中,胃肠道出血患者25例(22.5%),无胃肠道出血患者86例(77.5%)。胃肠道出血患者的白细胞、中性粒细胞以及中性粒细胞与淋巴细胞比值,儿童腹型过敏性紫癜患者胃肠道出血组白细胞计数、中性粒细胞计数,成年患者腹型过敏性胃肠道出血组中性粒细胞计数均明显高于无胃肠道出血组,差异有统计学意义(P<0.05)结论白细胞、中性粒细胞以及中性粒细胞与淋巴细胞比值指标水平联合测定可作为评估腹型过敏性紫癜患者有无胃肠道出血的实验室指标。
Objective To explore the predictive value of hematological indexes on gastrointestinal bleeding in patients with abdominal Henoch Schonlein purpura(HSP),so as to improve the level of early diagnosis and treatment.Methods The clinical data of111 patients with Henoch-Schonlein purpura with abdominal pain as the first manifestation from January 2013 to January 2019 were retrospectively analyzed.According to the symptoms of gastrointestinal bleeding,the patients were divided into the gastrointestinal bleeding group and the non-bleeding group.White blood cells,red blood cells,platelets,neutrophils,lymphocytes,eosinophils,mean platelet volume were measured in children and adults,and the neutrophil to lymphocyte ratio(NLR)and he platelets-to-lymphocytes ratio(PLR)were calculated.The correlation between the above laboratory indexes and gastrointestinal bleeding was analyzed.Results In 111 cases of abdominal type allergic purpura,25 cases(22.5%)had gastrointestinal bleeding and 86 cases(77.5%)had no gastrointestinal bleeding.The white blood cells,NLR in patients with gastrointestinal hemorrhage,white blood cell count and neutrophil count in children with abdominal HSP,and neutrophil count in adult patients with abdominal HSP were significantly higher than that of patients without gastrointestinal bleeding(P<0.05).Conclusion The combined determination of leukocytes,neutrophils and neutrophil/lymphocyte ratio can be used as laboratory indicators for evaluating gastrointestinal bleeding in patients with abdominal allergic purpura.
作者
马庆宇
张景展
梁俊琴
康晓静
MA Qingyu;ZHANG Jingzhan;LIANG Junqin;KANG Xiaojing(People′s Hospital of Xinjiang Uygur Autonomous Region,Xinjiang Key Laboratory of Dermatology Research(XJYS1707),Urumqi 830000,China)
出处
《新疆医学》
2021年第3期258-260,264,共4页
Xinjiang Medical Journal
基金
新疆维吾尔自治区人民医院院级课题(项目编号:20190106)
