摘要
目的探讨孕产妇下肢深静脉血栓形成(DVT)的血液学检验指标变化。方法选取2018年5月至2020年2月间在公主岭市妇幼保健计划生育服务中心分娩的孕产妇资料,52例孕产妇并发DVT为DVT组,选取同期103例孕产妇未发生DVT为对照组。收集并比较两组孕产妇入院时的一般资料;产后24~48 h的凝血功能指标[凝血酶原时间(PT)、部分活化凝血酶原时间(APTT)、纤维蛋白原(Fib)、凝血酶时间(TT)、血清D-二聚体(D-D)、血小板(PLT)]与血液流变学指标红细胞沉降率(ESR),并进行相关性分析。结果DVT组孕产妇PT、APTT和TT均低于对照组孕产妇;Fib、D-D、PLT和ESR均高于对照组孕产妇,差异有统计学意义(P<0.05);DVT组孕产妇的D-D水平与PT、APTT呈负相关(P<0.05)。结论加强对孕产妇凝血指标及血液流变学指标的监测,及时发现并干预DVT能够改善临床预后。
Objective To investigate the changes of hematological indexes of deep venous thrombosis(DVT)in pregnant women.Method The data of pregnant women who delivered in Gongzhuling Maternal and Child Health Care and Family Planning Service Center from May 2018 to February 2020 were selected as the DVT group,and 103 pregnant women without DVT in the same period were selected as the control group,52 pregnant women complicated with DVT were divided into DVT group.The general data of the two groups were collected and compared;the coagulation function indexes[prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(Fib),thrombin time(TT),serum D-dimer(D-D),platelet(PLT)]and hemorheological indexes of erythrocyte sedimentation rate(ESR)were collected and compared between the two groups.The correlation analysis was carried out.Result PT,APTT and TT in DVT group were lower than those in control group;Fib,D-D,PLT and ESR were higher than those in control group(P<0.05);D-D level in DVT group was negatively correlated with PT and APTT(P<0.05).Conclusion Strengthen the monitoring of coagulation and hemorheology indexes of pregnant and lying in women,detect and intervene DVT in time to improve the clinical prognosis.
作者
杨照一
李迎军
Yang Zhaoyi;Li Yingjun(Department of Laboratory,Gongzhuling Maternal and Child Health and Family Planning Service Center,Gongzhuling 136100,Jilin,China;Department of Laboratory,Central Hospital of Gongzhuling,Gongzhuling 136100,Jilin,China)
出处
《血管与腔内血管外科杂志》
2020年第5期435-438,共4页
Journal of Vascular and Endovascular Surgery
关键词
孕产妇
深静脉血栓形成
凝血指标
maternal
deep venous thrombosis
coagulation index
