摘要
核因子Y(nuclear factor-Y,NF-Y),又名为亚铁血红素激活蛋白或CCAAT结合因子,它是一种几乎存于所有真核生物中且进化比较保守的三聚体转录因子复合物,该复合物由NF-YA、NF-YB和NF-YC 3个亚基所组成。在酵母和动物中,每个亚基通常只有单个基因编码,而在植物中每个亚甲基都有多个基因编码,并且通常是形成三聚体复合物来发挥作用的。NF-Y在植物生长发育的多个阶段均发挥着重要的作用,如胚胎形成、根的生长、开花年龄及果实成熟等。另外,它也具有较强的抗逆能力。该文阐述了NF-Y单个亚基的结构和作用机制,并综述了该转录因子在植物生长发育过程中的重要作用。最后,对NF-Y的研究前景进行了展望。
NF-Y(nuclear factor-Y),also known as HAP(heme activator factor)or CBFCCAAT box binding factor.The NF-Y is trimeric transcription factor complex composed of NF-YA,NF-YB,and NF-YC subunits,and it is found almost in all eukaryotes.In yeast and animals,a single gene encodes each of the three NF-Y protein subunits.However,it generally have multiple genes encode each subunit in plants,and usually form a trimer complex to function.NF-Ys play important roles in the plant growth and development.Such as,regulating embryo synthesis,root growth,flowering age and fruit ripening,etc.In addition,it also has resistance to stress.Here,we mainly describe the structure of NF-Y single subunits and regulation mechanism of NF-Y,and reviews the important role of NF-Y in plant growth and development.Finally,the research prospects of NF-Y are prospected.
作者
李娟
高凯
安新民
LI Juan;GAO Kai;AN Xinmin(National Engineering Laboratory for Tree Breeding,NDRC,College of Biological Sciences and Biotechnology,Beijing Forestry University,Beijing 100083,China)
出处
《中国细胞生物学学报》
CAS
CSCD
2019年第12期2434-2442,共9页
Chinese Journal of Cell Biology
基金
转基因生物新品种培育重大专项(批准号:2018ZX08020002-002-004)
国家自然科学基金(批准号:31870652、31570661)
国家林业局科技发展中心(批准号:KJZXSA2018030)资助的课题.
关键词
植物
NF-Y
生长发育
抗逆性
plant
nuclear factor-Y
growth and development
stress tolerance