摘要
目的分析盐酸米诺环素软膏在牙周病患者种植牙修复围术期的应用效果。方法选取2021年1月-2022年12月我院收治的牙周病患者84例,采用随机数字表法将其分为对照组和观察组,每组各42例。所有患者均接受种植牙修复治疗,治疗期间给予对照组碘甘油治疗,给予观察组盐酸米诺环素软膏治疗。对比分析两组患者牙周指标、炎症因子水平以及临床相关指标水平。结果治疗前,牙周指标以及炎症因子水平组间比较,无明显差异(P>0.05);治疗后,牙周指标以及炎症因子水平组内比较治疗后低于治疗前,组间比较观察组低于对照组(P<0.05)。观察组患者一期种植牙修复伤口愈合率97.62%高于对照组85.71%,感染率2.38%低于对照组16.67%;观察组二期种植体丧失骨整合率4.76%低于对照组19.05%(P<0.05)。结论牙周病患者接受种植牙修复治疗期间给予盐酸米诺环素软膏进行干预效果理想,在改善牙周指标、降低牙周炎症反应以及提高伤口预后程度方面具有重要意义。
Objective:To analyze the effect of minocycline hydrochloride ointment in patients with periodontal disease during perioperative period.Methods:A total of 84 patients with periodontal disease admitted to our hospital from January 2021 to December 2022 were selected,and divided into the control group and the observation group by random number table method,with 42 cases in each group.All patients received dental implant restoration.During the treatment,patients in the control group were treated with iodine glycerine and patients in the observation group were treated with minocycline hydrochloride ointment.Periodontal indexes,inflammatory factors and clinical related indexes were compared between the two groups.Results:Before treatment,there were no significant differences in periodontal indexes and inflammatory factors among the groups(P>0.05).After treatment,intra-group comparison of periodontal indexes and inflammatory factors was lower than that before treatment,inter-group comparison:observation group was lower than control group(P<0.05).The wound healing rate of observation group was 97.62%higher than that of control group 85.71%,and the infection rate was 2.38%lower than that of control group 16.67%.The bone loss rate of the observation group was 4.76%lower than that of the control group(19.05%,P<0.05).Conclusion:The intervention effect of minocycline hydrochloride ointment on patients with periodontal disease during dental implant restoration is ideal,which has made great achievements in improving periodontal indexes,reducing periodontal inflammatory response and improving the prognosis of wound.
作者
彭晓红
PENG Xiao-hong(Xinyu People's Hospital,Xinyu Jiangxi 336600,China)
出处
《透析与人工器官》
2023年第3期45-48,共4页
Chinese Journal of Dialysis and Artificial Organs
关键词
盐酸米诺环素软膏
牙周病
种植牙修复
牙周指标
炎症因子
minocycline hydrochloride ointment
periodontal disease
dental implant restoration
periodontal index
inflammatory factor
