摘要
目的探讨血清β2微球蛋白(β2-MG)、胱抑素C(CysC)表达对透析患者肾功能评价的临床意义。方法选取40例血液透析患者的临床资料设为透析组,纳入同期于我院体检的40名健康人的临床资料设为对照组。比较两组CysC、β2-MG,利用ROC分析CysC、β2-MG预测透析患者肾功能损伤的价值。结果与对照组比较,透析组CysC、β2-MG增高(P<0.05)。CysC、β2-MG预测透析患者肾功能损伤的ROC曲线下面积分别为0.728、0.770。结论CysC、β2-MG可评估透析患者肾功能损伤程度。
ObjectiveThis paper aims to explore the clinical significance of the expression of serumβ2-microglobulin(β2-MG)and cystatin C(CysC)in evaluating renal function of dialysis patients.MethodsThe clinical data of 40 hemodialysis patients were set as dialysis group,and the clinical data of 40 healthy people who had physical examination in our hospital during the same period were set as control group.Compare CysC andβ2-MG between the two groups,and use ROC to analyze the value of CysC andβ2-MG in predicting renal function injury in dialysis patients.ResultsCompared with the control group,CysC andβ2-MG in dialysis group increased(P<0.05).The area under ROC curve of CysC andβ2-MG for predicting renal function injury in dialysis patients was 0.728 and 0.770,respectively.ConclusionCysC andβ2-MG can evaluate the degree of renal damage in dialysis patients.
出处
《透析与人工器官》
2016年第3期7-8,10,共3页
Chinese Journal of Dialysis and Artificial Organs
