摘要
目的研究不同批次中药制剂刺乌养心口服液的指纹图谱。方法采用HPLC法,以丹参素钠为参照物对10批刺乌养心口服液进行分析,并评价10批样品指纹图谱的相似度。结果在刺乌养心口服液指纹图谱中有20个共有峰,指认其中6个,相似度值为0.986~0.997。结论所建立的指纹图谱可为刺乌养心口服液的质量控制提供科学的参考。
Objective To study the fingerprints of different batches of traditional Chinese medicine preparation Ciwu Yangxin Oral Liquid.Methods Analyze 10 batches of Ciwu Yangxin liquid by HPLC with Danshensu sodium as the reference substance,and evaluate the similarity of the fingerprints of the 10 batches of samples obtained.Results There are 20 shared chromatographic peaks in the fingerprint spectrum of Ciwu Yangxin oral liquid,and 6 of them are identified,with similarity values ranging from 0.986 to 0.997.Conclusion The established fingerprint has good repeatability and stability,which can provide a scientific reference for the quality control of Ciwu Yangxin oral liquid.
作者
王威
李敬伟
赵旻
王淼
赵春杰
WANG Wei;LI Jingwei;ZHAO Min;WANG Miao;ZHAO Chunjie(School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,Liaoning,China;Department of Pharmacy,Chinese Peoples Armed Police Force Hospital of Beijing,Beijing,110027,China;School of Life Science and Biopharmaceuticals,Shenyang Pharmacelltical University,Shenyang 110016,China)
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2023年第2期173-177,218,共6页
Journal of Shenyang Pharmaceutical University
关键词
刺乌养心口服液
高效液相色谱
指纹图谱
Ciwu Yangxin oral liquid
high performance liquid chromatography
fingerprint
