摘要
目的探讨颅内动脉瘤支架辅助栓塞术中运用血栓弹力图(TEG)的临床价值。方法选择2015年1月—2018年12月期间北京市顺义区医院收治的156例颅内动脉瘤患者为研究对象,均行支架辅助弹簧圈栓塞术,然后将有无血栓相关并发症作为依据,将其分为无血栓组(n=135)和血栓组(n=21),运用TEG对抗血小板药物的疗效进行检测,并且运用Logistic回归对血栓并发症的相关危险因素进行分析。结果本组的156例患者中,21例发生血栓相关并发症,发生率为13.56%;与氯吡格雷相比,阿司匹林抵抗发生率明显较低,比较差异有统计学意义(P<0.05);同时,经Logistic多因素分析,发现血栓相关并发症的发生与阿司匹林抵抗和最大振幅值有关(P<0.05)。结论在颅内动脉瘤支架辅助栓塞术中,TEG可以对抗血小板药物的疗效进行有效检测,有助于预防血栓相关并发症。
Objective To study the clinical value of the use of thromboelastogram(TEG)in the treatment of intracranial aneurysm stent-assisted embolization.Methods 156 cases of intracranial aneurysm in the hospital from January 2015 to December 2018 were selected as the study object,the stent-assisted coil embolization was performed,and then there was no thrombus-related complication as the basis,and it was divided into the non-thrombus group(n=135)and the thrombus group(n=21).The efficacy of Antiplatelet drug was measured using TEG and the risk factors for thrombotic complications were analyzed by Logistic regression.Results Among the 156 patients,21 of the patients had a thrombus-related complication,and the incidence rate was 13.56%;the incidence of aspirin resistance was significantly lower in comparison with that of chloringray(P<0.05);at the same time,a logistic multi-factor analysis was performed.The occurrence of thrombus-related complications was found to be related to aspirin resistance and maximum amplitude(P<0.05).Conclusion In the treatment of intracranial aneurysm stent-assisted embolization,TEG can effectively detect the curative effect of platelet drug,and can be used to prevent the related complications.
作者
陈爱国
CHEN Aiguo(The Hospital of Shunyi District,Beijing 101300,China)
出处
《实用心脑肺血管病杂志》
2019年第S02期81-82,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
颅内动脉瘤
血栓弹力图
血栓
并发症
Intracranial Aneurysm
Thromboelastogram
Thrombus
Complications
