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氨磺必利联合丙戊酸钠治疗酒精所致精神障碍的临床效果及预后分析

Clinical effect and prognosis of amisulpride combined with valproate in the treatment of mental disorders caused by alcohol
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摘要 目的:分析应用氨磺必利与丙戊酸钠联合对酒精所致精神障碍患者的治疗效果。方法:随机选取2018年10月至2020年10月期间在我院接收的酒精所致精神障碍患者100例,按照治疗方法的不同平分为试验组(n=50例)和参照组(n=50例),分别给予氨磺必利与丙戊酸钠联合、氨磺必利进行治疗。结果:试验组治疗总有效率为96.00%(48/50),和参照组的80.00%(40/50)相比,具有统计学意义(P<0.05);阳性与阴性症状量表(Positive and Negative Syndrome Scale,PANSS)统计结果显示,组间差异显著(P<0.05)。两组患者的不良反应发生情况比较,具有统计学意义(P<0.05)。讨论:应用氨磺必利与丙戊酸钠联合对酒精所致精神障碍患者治疗,临床安全性较高,也可改善患者预后,值得推广。 Objective:To analyze the effect of amisulpride combined with sodium valproate in the treatment of mental disorders caused by alcohol.Methods:One hundred patients with mental disorders caused by alcohol in our hospital from October 2018 to October 2020 were randomly selected and equally divided into the experimental group(n=50 cases)and the reference group(n=50 cases)according to different treatment methods,and were given amisulpride and sodium valproate combined with amisulpride for treatment.Results:The total effective rate of the experimental group was 96.00%(48/50),compared with 80.00%(40/50)of the control group,with statistical significance(P<0.05);the statistical results of positive and Negative Syndrome Scale(PANSS)showed that the difference between the two groups was significant(P<0.05).The incidence of adverse reactions between the two groups was statistically significant(P<0.05).Discussion:The application of amisulpride combined with sodium valproate in the treatment of patients with mental disorders caused by alcohol has higher clinical safety and can also improve the prognosis of patients,which is worthy of promotion.
作者 梁经坤 Liang Jingkun(Chongqing Wushan People's Hospital)
出处 《保健文汇》 2020年第12期281-282,共2页 Health Literature
关键词 酒精所致精神障碍 氨磺必利 丙戊酸钠 效果 预后 Mental disorder caused by alcohol Amisulpride Sodium valproate Effect Prognosis
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