摘要
目的探讨徐振晔教授治疗肺癌脾肾两虚证的临床用药规律和学术思想。方法建立Access数据库,收集徐振晔教授肺癌临床病案,运用SPSS 21.0统计软件对处方药物进行聚类分析和因子分析。结果共收集徐教授治疗肺癌脾肾两虚证临床病案310份,共使用中药140种,常用中药39种,平均处方用药18.8味,药物集中,处方精炼。处方中核心药物为石见穿、生黄芪、炒白术、重楼、黄精、鸡内金、灵芝、淫羊藿、蜂房、山慈菇、党参等。并随症选用太子参、茯苓、白扁豆等健脾补肺;徐教授始终不忘顾护胃气,常用鸡内金、炒谷芽、炒麦芽等药物健胃助运;肺肾阴亏者还加用麦冬、北沙参等;失眠焦虑患者常用炙甘草、淮小麦、大枣、知母、灯心草、酸枣仁;咳嗽痰多气喘患者多使用杏仁、芦根、枇杷叶;脘腹胀满、纳呆呕恶者加用黄连、木香。瘀血证兼有肢体麻木者加川芎、桂枝。结论徐振晔教授治疗脾肾两虚证主肺癌以健脾补肺、滋肾养精,兼以攻毒散结,佐以顾护胃气。攻补兼施,扶正祛邪相结合。聚类分析和因子分析为名老中医学术经验传承提供客观的研究依据,有助于中医药发展。
Objective To analyze and study the clinical medication rule and academic thought of Professor Xu Zhenye in the treatment of spleen and kidney deficiency syndrome of lung cancer.Methods The Access database was established to collect the clinical medical records of Professor Xu Zhenye's treatment of lung cancer,and the prescription drugs were analyzed by cluster analysis and factor analysis using SPSS 21.0 statistical software.Results A total of 310 clinical cases of Professor Xu's treatment of lung cancer with deficiency of spleen and kidney were collected.A total of 140 kinds of traditional Chinese medicines were used,39 kinds of traditional Chinese medicines were commonly used,with an average of 18.8 prescriptions.The drugs were concentrated and the prescriptions were refined.The core drugs in the prescription are salvia chinensis,raw Astragalus,fried Atractylodes macrocephala,Paris polyphylla,Polygonatum,membranes of chicken gizzards,Ganoderma lucidum,epimedium,beehive,arrowhead mushroom,Codonopsis pilosula,etc.Radix Pseudostellariae,Poria cocos and white lentils were selected to strengthen the spleen and lung;Professor Xu never forgets to protect stomach qi.He often uses drugs such as chicken inner gold,fried grain sprouts and fried malt to strengthen the stomach and help transport;Those with deficiency of lung and kidney Yin also use Ophiopogon japonicus and North ginseng;Insomnia and anxiety patients often use roasted licorice,Huai wheat,jujube,Anemarrhena,rushes and sour jujube kernel;Patients with cough,phlegm and asthma often use almonds,reed roots and loquat leaves;Those with abdominal distension,poor appetite,nausea and vomiting should be added with Coptis chinensis and incense.For those with blood stasis syndrome accompanied by limb numbness,add Chuanxiong and Cassia twig.Conclusion Professor Xu Zhenye's treatment of lung cancer with spleen and kidney deficiency syndrome,which is mainly to strengthen the spleen and lung,nourish kidney essence,attack poison and disperse knot,and take care of stomach qi.It embodies the combination of attacking and tonifying and supporting the right and dispelling the evil.Cluster analysis and factor analysis provide objective research basis for the inheritance of famous and old traditional Chinese medicine academic experience,which is conducive to the development of traditional Chinese medicine.
作者
许海柱
徐振晔
陈佩晶
Xu Haizhu;Xu Zhenye;Chen Peijing(Longhua Medical College of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Huadong Hospital Affiliated to Fudan University,Shanghai 200040,China;Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine,Shanghai 200032,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2023年第4期1217-1223,共7页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家中医药管理局2022年全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号):徐振晔教授传承工作室,负责人:邓海滨
关键词
徐振晔教授
肺癌
聚类分析
因子分析
用药规律
Professor Xu Zhenye
Lung cancer
Cluster analysis
Factor analysis
Medication rule
