摘要
目的归纳、总结基于"咽肾相关"理论中医药对IgA肾病的认识及干预治疗。方法通过检索中国期刊全文数据库、维普期刊数据库和万方资源数据库及PubMed近十年关于从咽论治IgA肾病的相关文献,进行归纳、整理、分析、总结得出结论。结果咽肾在生理病理上有着密切的联系;肾元亏虚是IgA肾病的核心病机,邪毒蕴结咽喉是IgA肾病主要诱因;应用补肾健脾,解毒利咽或滋阴利咽中药治疗可改善IgA肾病患者的临床症状,降低24 h尿蛋白定量、尿红细胞计数、血肌酐等指标,从而延缓病情的进展。结论基于"咽肾相关"理论中医药治疗IgA肾病可改善患者生活质量,提高临床疗效,起到保护肾脏的作用。
Objective To summarize and conclude the understanding and intervention treatmentof TMC in IgA nephropathy based on the theory of"pharyngeal and kidney".Methods Literatures about treating IgA nephropathy from pharyngeal in the past ten years were collected by searching the electronic databases including CNKI,VIP and WanFang Data,PubMed.And then concluded,sorted out,analyzed and summarized the conclusions.Results The pharyngeal and kidney are closely related physiologically and pathologically.The core pathogenesis of IgA nephropathy is Renal deficiency and the main cause of IgA nephropathy is Evil poison binding the throat.It could relieve clinical symptoms,reduce indicators of 24 h urinary protein quantification,urinary red blood cell count,and blood creatinine of IgA nephropathy with TMC of notifying kidney and spleen,toxic to the pharynx or nourishing Yin to the pharynx and delay the progression of the disease.Conclusion TMC can improve the quality of life and clinical efficacy of IgA nephropathy based on the theory of"pharyngeal and kidney",thus taking effect in protecting kidney.
作者
赵洁
孟立锋
莫超
蓝芳
梁春琴
史伟
Zhao Jie;Meng Lifeng;Mo Chao;Lan Fang;Liang Chunqin;Shi Wei(Graduate School of Guangxi University of Chinese Medicine,Nanning 530001,China;Nephrology Department of First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2020年第4期1148-1152,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委员会地区科学基金项目(81560761):间隙连接蛋白43调控PI3K/Akt/mTOR通路介导腹膜间皮细胞EMT机制及健脾益肾方干预效应,负责人:孟立锋
国家自然科学基金委员会地区科学基金项目(81860838):内质网应激通路IREIα-XBP1诱导腹膜间皮细胞自噬在MET中的发生机制及健脾益气方的干预效应,负责人:孟立锋
广西2017年十大工程项目(桂卫中医发【2017】2号):史伟名中医传承工作室,负责人:史伟
关键词
IGA肾病
咽肾相关理论
中医药
IgA nephropathy
the theory of pharyngeal and kidney
Traditional Chinese Medicine