摘要
目的:分析腧穴揿针疗法治疗青海地区慢性阻塞性肺疾病加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)(痰浊阻肺证)患者的临床价值。方法:选取2019年7月~2020年7月于我院收治的83例AECOPD(痰浊阻肺证)患者的临床资料,根据不同治疗方法分研究组(n=43,予以腧穴揿针疗法治疗)和对照组(n=40,常规治疗)。对比两组患者临床疗效、炎性因子[白介素6(interleukin-6,IL-6)、肿瘤坏死因子-α(Tumor necrosis factorα,TNF-α)水平、C反应蛋白(C-reaction protein,CRP)]、中医证候、慢性阻塞性肺病评估测试(COPDAssessment TestTM,CAT)评分、呼吸困难指数[改良英国MRC呼吸困难指数(modified british medical research council,mMRC)]、不良反应。结果:研究组患者总有效率(93.02%)vs明显高于对照组(75.00%)(P<0.05);治疗后两组IL-6、CRP及TNF-α均较治疗前降低,但研究组炎性因子水平在治疗后明显低于对照组(P<0.05);两组患者治疗后中医证候评分及CAT评分均较治疗前降低,研究组明显较对照组低(P<0.05);治疗前,两组mMRC量表评分处于3、4级患者居多(P>0.05),治疗后,两组mMRC量表评分以0~2级者占多数,且研究组处于0~2级患者显著高于对照组(P<0.05);两组治疗期间均未出现严重不良反应。结论:对青海地区AECOPD(痰浊阻肺证)患者予以腧穴揿针疗法治疗临床疗效佳,可显著抑制炎性因子,改善患者呼吸困难及肺部情况,值得临床推广应用。
Objective:To analyze the clinical value of press-needle in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)(syndrome of turbid phlegm obstructing lung)patients in Qinghai.Methods:The clinical data of 83 patients with AECOPD(syndrome of turbid phlegm obstructing lung)admitted to our hospital from 2019 to July 2020 were selected and divided into study group(n=43,treated by press-needle therapy)and control group(=40,conventional treatment)according to different treatment methods.The clinical efficacy,inflammatory factors[interleukin-6(IL-6),tumor necrosis factorα(TNF-α)levels,and C-reaction protein(CRP)],TCM symptoms,COPDAssessment Test(CAT)score,dyspnea index[modified british medical research council(mMRC)],and adverse reactions were compared between the two groups.Results:The total effective rate of patients in the study group was significantly higher than that in the control group(93.02%vs 75.00%)(P<0.05).After treatment,the levels of IL-6,CRP and TNF-αin the two groups were lower than those before treatment,but the levels of inflammatory factors in the study group were significantly lower than those in the control group after treatment(P<0.05).The TCM symptom scores and CAT scores of the patients in the two groups after treatment were lower than those before the treatment,and the scores of the study group were significantly lower than those of the control group(P<0.05).Before treatment,most of patients in the two groups in terms of mMRC scale scores were in grades 3 and 4(P>0.05).After treatment,most of the patients in the two groups scored 0 to 2 on the mMRC scale,and the patients in the 0-2 grades of the study group were significantly more than those in the control group(P<0.05).There were no serious adverse reactions in the two groups during the treatment.Conclusion:The clinical efficacy of press-needle therapy for patients with AECOPD(syndrome of turbid phlegm obstructing lung)in Qinghai has good clinical effect.It can significantly suppress inflammatory factors and improve the patient's dyspnea and lung conditions.It is worthy of clinical application.
作者
武胜举
赵永祥
姚惠青
WU Shengju;ZHAO Yongxiang;YAO Huiqing(Department of Lung disease division,Qinghai Provincial Hospital of Traditional Chinese medicine,Xining Qinghai 810000,China)
出处
《四川中医》
2023年第4期188-191,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
青海省中医院科学技术研究项目(编号:2020YN13)
关键词
慢性阻塞性肺疾病加重期
痰浊阻肺证
青海地区
腧穴揿针疗法
Acute exacerbation of chronic obstructive pulmonary disease
Syndrome of turbid phlegm obstructing lung
Qinghai area
press-needle therapy
